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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3-MEC

    Aliases: 3-meec

    Stimulant Research-chemical

    Summary TheDrug.Wiki TripSit

    3-Methylethcathinone (3-MEC, 3-MeEC) is the 3-methyl positional isomer of 4-MEC and a close analogue of mephedrone. It emerged on the grey market around 2010-2012 and is usually encountered as an off-white crystalline powder. Pharmacological data are extremely sparse; limited in vitro assays suggest it acts primarily as a dopamine/norepinephrine releaser and reuptake inhibitor with weaker serotonergic activity than 4-MMC or MDMA.

    Dose Information TheDrug.Wiki TripSit

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-175mg 175-250mg 250mg+
    Insufflated 25-50mg 50-100mg 100-150mg 150mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit

    ROA Onset Comeup Peak Offset After Effects
    Oral 30-90 min 45-90 min 1-2 hrs 30-60 min 2-5 hrs
    Insufflated 5-10 min 10-15 min 20-40 min 30-60 min 1-3 hrs
    Rectal 10-20 min 15-30 min 45-90 min 30-60 min 2-4 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 3.6
    Moderate 4/10

    Moderate sensory enhancement and stimulation with low euphoria and empathy

    Empathy / Social Openness ×3
    2
    enhanced sociability
    Euphoria / Mood Elevation ×2
    3
    euphoria
    Stimulation ×1
    6
    physical stimulation wakefulness increased heart rate
    Sensory Enhancement ×1
    7
    tactile enhancement color enhancement increased libido
    Stimulant 3.9
    Moderate 4/10

    Strong anxiety/jitters with mild stimulation and focus, low euphoria

    Stimulation / Energy ×3
    5
    physical stimulation wakefulness
    Euphoria / Mood Lift ×2
    3
    euphoria
    Focus / Productivity ×2
    5
    focus enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety jitteriness bruxism increased heart rate jaw tension vasoconstriction +1 more
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 3-MEC
    View methodology →

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Effects TheDrug.Wiki

    Positive
    • Physical stimulation
    Negative
    • Bruxism
    • Jaw tension
    • Pupil dilation
    • Increased heart rate
    • Vasoconstriction
    • Jitteriness
    • Sweating
    • Urinary retention
    • Comedown fatigue
    Neutral
    • Temperature elevation
    Positive
    • Euphoria
    • Enhanced sociability
    • Focus enhancement
    • Wakefulness
    Negative
    • Anxiety
    • Compulsive redosing
    • Post-use anhedonia
    Neutral
    • Increased talkativeness
    • Time distortion
    • Thought acceleration
    Positive
    • Tactile enhancement
    • Increased music appreciation
    • Increased libido
    • Tracers
    • Color enhancement
    • Pattern recognition enhancement
    Negative
    • Appetite suppression
    • Light sensitivity
    • Dehydration
    • Disinhibition

    Combinations TripSit

    3-MEC's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki