3-MeO-PCE
Aliases: Methoxieticyclidine, Methoxyieticyclidine, 3meopce
Categories
Summary
3-MeO-PCE is a potent dissociative with a significantly higher risk of inducing mania, delusions, and psychosis than other dissociatives such as ketamine or MXE. It is extremely stimulating and carries a pronounced tendency toward compulsive redosing, especially when smoked or vaporized. Due to its high potency, volumetric liquid dosing is strongly recommended. Users should avoid multi-day binges and high dosages, as these dramatically increase the risk of severe adverse psychological effects including psychotic episodes.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 4-8mg | 8-15mg | 15-25mg | 25mg+ |
| Insufflated | 3-6mg | 6-12mg | 12-20mg | 20mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 30-90 min | 1.0-2.0 hrs | 2.0-3.0 hrs | 1.0-2.0 hrs | 4.0-48.0 hrs | 3.0-5.0 hrs |
| Insufflated | 3-15 min | 45-90 min | 1.5-2.0 hrs | 45-60 min | 4.0-48.0 hrs | 3.0-5.0 hrs |
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Cross-tolerance
Effects
Positive
- Stimulation
- Physical euphoria
- Analgesia
- Nausea suppression
- Pain relief
- Creativity enhancement
Negative
- Respiratory depression
- Increased heart rate
- Increased blood pressure
- Increased perspiration
- Seizure
- Physical disconnection
- Difficulty urinating
- Restless legs
- Spontaneous bodily sensations
Positive
- Cognitive euphoria
- Conceptual thinking
- Anxiety suppression
- Unity and interconnectedness
- Immersion intensification
- Increased introspection
Negative
- Depersonalization
- Derealization
- Mania
- Delusions
- Delusions of sobriety
- Compulsive redosing
- Psychosis
- Motor control loss
- Memory suppression
- Cognitive disconnection
- Dizziness
- Delusion
- Thought deceleration
- Amnesia
- Dissociation
- Consciousness disconnection
- Time distortion
- Perspective distortion
- Physical autonomy
Positive
- Tactile enhancement
- Perception of bodily lightness
- Bodily control enhancement
- Acuity enhancement
- Synaesthesia
- Color enhancement
- Visual acuity enhancement
- Increased music appreciation
Negative
- Disinhibition
- Spatial disorientation
- Pattern recognition suppression
- Double vision
- Dehydration
- Tactile suppression
- Appetite suppression
- Visual acuity suppression
- Auditory acuity suppression
- Visual disconnection
- Internal hallucinations
- Auditory hallucination
- Auditory distortion
- Scenery slicing
- Environmental cubism
- Changes in felt gravity
- Internal hallucination
- Autonomous entity
- Olfactory hallucination
- Optical sliding
- Perspective hallucination
- Tactile intensification
- Visual processing deceleration