3,4-CFPP
Aliases: 3,4-cfp, 3cl-4f-p, Kleferein, 3-chloro-4-fluoro-piperein
Categories
Summary
Very little pharmacological or toxicological data exists. Based on structural similarity to mCPP and TFMPP, this compound likely acts as a non-selective serotonin receptor agonist and serotonin releaser. These phenylpiperazines are notorious for producing nausea, migraines, anxiety, and dysphoria rather than euphoria. Severe reactions including hypertension, hyponatremia, and seizures have been reported with related piperazines. The synthesis and anorexigenic properties were described in a 1972 patent, but human metabolism, effective dosing, and long-term safety remain largely uncharacterized.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects |
|---|---|---|---|---|
| Oral | 20-60 min | 1-3 hrs | 1-2 hrs | 1-6 hrs |
| Insufflated | 5-15 min | 1-3 hrs | 1-2 hrs | 1-6 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute tolerance; longer for full reset
Effects
Positive
- Physical stimulation
Negative
- Restlessness
- Insomnia
- Teeth grinding
- Pupil dilation
- Increased perspiration
- Temperature regulation suppression
- Nausea
- Headache
- Pupil Dilation
Positive
- Mood lift
- Empathy enhancement
- Alertness enhancement
- Empathy Enhancement
- Euphoria
Negative
- Anxiety
- Dysphoria
- Drowsiness
- Talkativeness
- Feelings of Impending Doom
Positive
- Tracers
- Color Enhancement
Negative
- Light sensitivity
- Appetite Suppression
- Decreased Libido
- Dehydration
- Visual distortions
- Closed-Eye Visuals
- Visual Drifting
- Perception of Bodily Heaviness