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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3,4-DMMC Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 3 corroborating sources
    • 2 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Aliases: M2, Ocean

    Stimulant Research-chemical

    Summary dose.wiki

    3,4-DMMC was first detected in Europe in 2010 and marketed under street names "Ocean" and "M2" as a mephedrone replacement. Potency is noticeably lower than mephedrone; users describe effects as "blunted" or "foggy." Nasal administration produces pronounced chemical burn and rhinorrhea. Pharmacodynamic data show similar affinity at norepinephrine and serotonin transporters but weaker dopamine transporter activity compared to mephedrone, resulting in mild empathogenic effects and potentially higher cardiovascular strain.

    Dose Information dose.wiki Drugs.Wiki

    Dose basis. All ranges are user-reported and unverified by clinical studies; start low, use a 0.001 g scale, and avoid redosing ‘on the come-up’. User reports consistently describe significant nasal irritation and nosebleeds; consider oral ROA instead and follow safer-s sniffing practices if you proceed. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Oral 100-150mg 150-250mg 250-350mg 350mg+
    Insufflated 30-60mg 60-120mg 120-180mg 180mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki Drugs.Wiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-30 min 30-60 min 1-2 hrs 60 min 2-8 hrs 2.75-4.5 hrs
    Insufflated 5-10 min 15-30 min 30-60 min 60 min 2-8 hrs 1.83-2.67 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Empathogen 6.3
    Strong 6/10

    Strong sensory enhancement with moderate stimulation and euphoria, mild empathy

    Empathy / Social Openness ×3
    5
    empathy sociability enhancement
    Euphoria / Mood Elevation ×2
    6
    cognitive euphoria euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    10
    tactile enhancement music enhancement color enhancement increased libido
    Stimulant 3.9
    Moderate 4/10

    Strong anxiety/jitters with moderate euphoria, mild stimulation, low focus

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    6
    cognitive euphoria euphoria
    Focus / Productivity ×2
    2
    thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate vasoconstriction
    View methodology →

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 3,4-DMMC there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "3,4-DMMC (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    3,4-DMMC
    Unit
    mg
    Description 
    3,4-DMMC
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): threshold 50 · light 100-150 · common 150-250 · strong 250-350 · heavy 350+
Insufflated dose (mg): threshold 20 · light 30-60 · common 60-120 · strong 120-180 · heavy 180+

Oral duration: onset 15-30m · come-up 0.5-1h · peak 1-2h · offset 1h · total 2.75-4.5h · after-effects 2-8h
Insufflated duration: onset 5-10m · come-up 15-30m · peak 0.5-1h · offset 1h · total 1.83-2.67h · after-effects 2-8h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 200 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Effects dose.wiki

    Positive
    • Stimulation
    Negative
    • Teeth grinding
    • Vasoconstriction
    • Increased heart rate
    • Increased blood pressure
    • Pupil dilation
    • Increased perspiration
    • Insomnia
    Neutral
    • Nasal irritation
    • Decreased appetite
    Positive
    • Cognitive euphoria
    • Sociability enhancement
    • Empathy
    • Euphoria
    • Wakefulness
    Negative
    • Compulsive redosing
    • Cognitive fog
    • Anxiety
    • Depression
    Neutral
    • Thought acceleration
    Positive
    • Music enhancement
    • Tactile enhancement
    • Increased libido
    • Increased music appreciation
    • Tracers
    • Color enhancement
    Negative
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    • Disinhibition

    Combinations

    Cross-Check 3,4-DMMC with another substance

    3,4-DMMC's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki