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    Disclaimer
    ⚠ PCP and its analogues are potent dissociatives with significant risk of psychosis, violent behavior, and overdose. Effects are highly unpredictable and dose-sensitive.
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    3,4-MD-PCP

    Aliases: Mdpcp

    Dissociative Research-chemical

    Summary TheDrug.Wiki

    NMDA receptor affinity approximately 62 nM, placing potency between 3-MeO-PCP and ketamine. Users describe warm, chameleonic dissociation that varies dramatically with dose and setting, ranging from lucid sociability at low doses to overwhelming mania at high doses. The dose-response curve is steep above 40 mg.

    Perspectives

    “Smooth, insightful, a bit manic, colorful, warm, euphoric, and sociable. An extremely interesting novelty with significant potential as a multifunctional dissociative.”

    Dose Information TheDrug.Wiki

    ROA Light Common Strong Heavy
    Oral 5-20mg 20-40mg - -
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 15-45 min 30-60 min 2-4 hrs 3-5 hrs 2-8 hrs
    Insufflated 4-15 min 15-30 min 2-4 hrs 3-5 hrs 2-8 hrs

    Effect Profile

    1 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 6.6
    Strong+ 7/10

    Strong dissociative depth and motor impairment with mild insight and mania

    Dissociative Depth ×3
    10
    depersonalization derealization physical disconnection cognitive disconnection visual disconnection spatial disorientation +2 more
    ⚠ Mania / Compulsion ×1
    4
    disinhibition stimulation
    Insight / Novel Thought ×2
    5
    conceptual thinking analysis enhancement
    ⚠ Motor / Sensory Impairment ×1
    10
    motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection +1 more
    Based on reports from:
    Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 3,4-MD-PCP
    View methodology →

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Effects TheDrug.Wiki

    Positive
    • Physical euphoria
    • Stimulation
    • Analgesia
    • Pain relief
    Negative
    • Nystagmus
    • Numbness
    • Loss of balance
    • Nausea
    Neutral
    • Physical disconnection
    • Sedation
    Positive
    • Analysis enhancement
    • Cognitive euphoria
    • Conceptual thinking
    Negative
    • Cognitive disconnection
    • Motor control loss
    • Depersonalization
    • Derealization
    • Amnesia
    • Memory suppression
    Neutral
    • Time distortion
    Positive
    • Tactile enhancement
    • Colour enhancement
    • Increased music appreciation
    Negative
    • Tactile suppression
    • Disinhibition
    • Spatial disorientation
    • Double vision
    Neutral
    • Visual drifting
    • Visual disconnection
    • Auditory distortion

    Combinations TripSit

    3,4-MD-PCP's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 Bluelight 📖 PsychonautWiki