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    3,4-MDPV Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented

    Aliases: MDPV

    Summary

    3,4-MDPV is a stimulant cathinone. Reported effects include euphoria, color enhancement, time distortion, and wakefulness. Limited data is available on its dosage and safety profile.

    Dose Information PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 4-8mg 8-14mg 14-25mg 25mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 15-30 min 1-4 hrs 0.5-2 hrs 2-48 hrs 2-7 hrs

    Effect Profile

    105 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 105 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 8.8
    Intense+ 9/10

    Strong stimulation, euphoria, focus, and anxiety/jitters

    Stimulation / Energy ×3
    10
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    10
    physical euphoria euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    10
    focus enhancement motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes 3,4-MDPV, but its built-in data can be thinner than ours. Importing this file adds a separate "3,4-MDPV (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "3,4-MDPV (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Effects Erowid

    Aggregated from 105 Erowid experience reports

    Positive Effects 10

    Stimulation 57.1% 70%
    Euphoria 54.3% 70%
    Focus Enhancement 35.2% 70%
    Empathy 25.7% 70%
    Music Enhancement 20.0% 70%
    Tactile Enhancement 18.1% 70%
    Color Enhancement 12.4% 70%
    Creativity Enhancement 10.5% 70%
    Introspection 8.6% 70%
    Body High 4.8% 70%

    Adverse Effects 13

    Anxiety 49.5% 70%
    Increased Heart Rate 25.7% 70%
    Confusion 19.0% 70%
    Headache 12.4% 70%
    Jaw Clenching 12.4% 70%
    Psychosis 11.4% 70%
    Nausea 11.4% 70%
    Pupil Dilation 10.5% 70%
    Muscle Tension 9.5% 70%
    Sweating 8.6% 70%
    Motor Impairment 6.7% 70%
    Memory Suppression 2.9% 70%
    Appetite Suppression 2.9% 70%

    Combinations

    Cross-Check 3,4-MDPV with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 8 reports 2 positive 3 neutral 3 cautionary visit
    Pretty Much Zero Fun cautionary exp #92198

    Helluva Drug I'm 21, male, pretty basic experience with psychedelics. LSD, mushrooms, weed, opiates, a couple 2c's, DMT, MDMA. MDPV does not belong in the same category as the aforementioned substances. It is one hell of a drug, but it is by NO means recreational.

    cryptix420 · MDPV · insufflated
    I Love This Stimulant positive exp #92092

    MDPV Amazing I have purchased pure MDPV multiple times and can say it is not my favorite drug but the price and high is great. Everyone seems to hate on MDPV. I have gone through grams I came down. I have vaporized insufflated and orally.

    NoOneImportant · MDPV · repeated
    One Hell of a Drug positive exp #86062

    I had the most amazing experience on this drug. In retrospect, I would do this over and over again. I can see why it is said to be highly addictive, feeling the need to redose constantly as my friends all tried more and more of the chemical.

    Go Beats · MDPV · repeated insufflated
    The Full Ride cautionary exp #90171

    I sought to purchase either Prolintane HCl or MDPV to experience an uncommon stimulant with my friend Drew. MethyleneDioxyPyroValerone won. Got lucky with Prolintane HCl just once, which I predict to be the next wonder designer drug that catches on as its legal worldwide and OTC in Spain.

    GewaltHaber · MDPV · insufflated / insufflated / insufflated / insufflated
    Got That Moxy neutral exp #89659

    Very rarely do I ever feel compelled to share my experiences with masses of people, but this is one that I feel very good about. Methylenedioxypyrovalerone is pretty much unheard of in most drug cultures. I guess one could say it is the 'new kid on the block', though pyrovalerone has been on the market since the 60's.

    That Guy · MDPV · repeated insufflated
    Not Exactly a Good Time neutral exp #85947

    My experiments to date with MDPV have left me feeling rather unimpressed. It’s adequate for use as a stimulant and while I enjoy the primary effects of the substance, the harsh come-down usually renders the entire experience not worth the ultimate punishment.

    Calipsonic · MDPV · 10 mg insufflated / 10 mg insufflated / 7 mg insufflated / 4 mg insufflated
    Most Devilish Powdered eVil cautionary exp #90252

    Insidious Neurological Poison - AVOID AT ALL COSTS - A DIRE WARNING (M)ost (D)evilish (P)owdered E(V)IL If there ever was a substance that could make anyone a zombie . . .

    Anonymous · MDPV · 5 mg insufflated / 4 mg insufflated / 1 mg oral / 10 mg insufflated
    The Most Ridiculous Day of My Life neutral exp #91064

    [Erowid Note: Cannabis substitute "spice" type smoking blends, "Bath salts", "plant food", "incense", "tea" and similar products generally do not accurately list psychoactive ingredients or dosage on their packaging. Analysis has revealed that ingredients in a single product of this type may vary over time.

    lucky · MDPV · 1 line insufflated / repeated oral / smoked
    Bluelight 3 threads 3 neutral visit
    Mdpv Friends The Endless Bag And The Journey That Still Continues neutral

    An experience within an experience - " synchronicity is playing hide and seek. " __________________________________ For such a long time I've been in a haze, not by fault of one particular incidance but because my 'box' had been trampled on.

    scraped 2026-03-14
    Mdpv Inexperienced User neutral

    My First Experience With MDPV, And Beyond! Thoughts, mistakes, things that worked for me, and more! Initially intended to post on the MDPV Mega-thread, but I think it would be better off here as it is more Trip Report than General discussion/questions/info.

    scraped 2026-03-14
    Mdpv Inexperienced Eyeballed Dose Discomfort At Work neutral

    Hello, I have used tiny amounts of MDPV on a few occasions. I do not at the moment have 0.001g scales although they are on their way and should be with me soon. Although I do not have any scales that can measure out 10mg accurately, I felt that I could eyeball the dose on the first few occasions.

    scraped 2026-03-14

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