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    3F-PCP molecular structure

    3F-PCP Stats & Data

    3-fluoro-pcp
    NPS DataHub
    MW261.38
    FormulaC17H24FN
    CAS89156-99-0
    IUPAC1-[1-(3-fluorophenyl)cyclohexyl]piperidine
    SMILESFc1cccc(c1)C1(CCCCC1)N1CCCCC1
    InChIKeyPFPLGKFWWBXTNP-UHFFFAOYSA-N
    Arylcyclohexylamines; 2021/6. Von Arylcyclohexylamin abgeleitete Verbindungen; 2022/6. Von Arylcyclohexylamin abgeleitete Verbindungen
    Psychoactive Class Dissociative
    Half-Life ~10–18 h (very approximate; inferred from forensic case timelines; human PK studies lacking)

    Receptor Profile

    Receptor Actions

    Antagonists
    NMDA receptor antagonist (noncompetitive)

    History & Culture

    3F-PCP is a relatively recent addition to the novel dissociative market. The compound was first analytically identified in Slovenia in October 2020, marking its initial detection by drug monitoring services. As a designer arylcyclohexylamine, it emerged as part of the ongoing development of novel phencyclidine derivatives intended for recreational use.

    Effect Profile

    Curated + 1 Reports
    Dissociative 6.6

    Strong dissociative depth and motor impairment with mild insight and mania

    Dissociative Depth×3
    10
    Mania / Compulsion×1
    4
    Insight / Novel Thought×2
    5
    Motor / Sensory Impairment×1
    10

    Duration Timeline

    Bluelight
    Onset Comeup Peak Offset After Effects
    Oral
    19 minutes - 1.0 hours
    30 minutes - 1.0 hours
    1-3 hours
    2-4 hours
    4-8 hours
    Sublingual
    19 minutes - 1.0 hours
    30 minutes - 1.0 hours
    1-3 hours
    2-4 hours
    4-8 hours
    Insufflated
    4-10 minutes
    19-40 minutes
    1-3 hours
    2-4 hours
    4-8 hours
    Rectal
    10-30 minutes
    30 minutes - 1.0 hours
    1-3 hours
    2-4 hours
    4-8 hours
    Intramuscular
    1-4 minutes
    10-19 minutes
    1-3 hours
    2-4 hours
    4-8 hours

    Community Effects

    TripSit
    Positive
    dissociation stimulation
    Negative
    mania confusion

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    ~10–18 h (very approximate; inferred from forensic case timelines; human PK studies lacking)
    Addiction Potential
    Moderate to high (psychological). Rapid tolerance and episodes of manic euphoria/“false sobriety” reported, which can encourage redosing binges.

    Tolerance Decay

    Full tolerance 0h Half tolerance 3d Baseline ~10d

    Rapid tolerance within a session is commonly reported for PCP‑class dissociatives; cross‑tolerance across the class is expected. Estimates above are anecdotal aggregates and vary substantially by individual, dose, and redose pattern.

    Cross-Tolerances

    PCP
    70% ●○○
    Ketamine
    50% ●○○
    Other arylcyclohexylamines
    70% ●○○

    Experience Report Analysis

    Erowid
    1 Reports
    2020–2020 Date Range

    Demographics

    Gender Distribution

    Reports Over Time

    Legal Status

    Country Status Notes
    Hungary Illegal Classified as a controlled substance in April 2021. Production, distribution, and possession are prohibited under Hungarian drug control legislation.

    Harm Reduction

    drugs.wiki

    • Identification and purity: 3‑F‑PCP first appeared in Europe (Slovenia) in late 2020; multiple user communities have since noted batch variability and occasional mislabeling as other PCP analogues (e.g., 3‑Cl‑PCP), making lab‑based drug checking highly advisable. Reagent tests are non‑specific for the class; GC/MS or FTIR is preferable via local drug‑checking services.

    • Onset and redosing: Several reports emphasize a slow or uneven come‑up—especially orally/sublingually—so avoid topping up for at least 2–3 hours to prevent accidental overdosing into manic confusion.

    • Nasal harm reduction: Insufflation commonly causes severe burn and caustic drip; use finely powdered, tiny test lines, allow long gaps between bumps, and rinse with sterile saline after sessions to reduce tissue damage and epistaxis risk.

    • Functional impairment and injury risk: PCP‑class dissociatives can produce profound analgesia, proprioceptive distortion, and overconfidence. Do not cook, drive, swim, or climb during the session and for the entire residual period. Use a sober sitter for strong doses.

    • Mental health cautions: High or repeated doses increase risk of acute psychosis‑like states (paranoia, delusions, disinhibition). Individuals with psychosis‑spectrum or bipolar histories should avoid.

    • Tolerance/compulsion: Rapid tolerance accrues within a session and over days. Spacing sessions by 10–14 days reduces escalation.

    • Hydration and temperature: Maintain gentle hydration and a cool environment; avoid strenuous activity—stimulant‑like activation plus dissociation is associated with overheating and accidents in PCP‑class use.

    • IM use is high‑risk: Variable solubility, unknown excipients, and pH can cause tissue injury or abscess; many find IM doses deceptively strong and dysphoric beyond low–moderate ranges. Prefer non‑injecting routes.

    References

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