3F-PCP
Aliases: 3-fluoro-pcp
Summary
3-Fluoro-PCP is a potent dissociative anesthetic structurally related to PCP and 3-MeO-PCP, characterized by stimulating dissociation with a steep dose-response curve. First detected in Slovenia in October 2020 and now controlled in multiple jurisdictions. Features sub-micromolar affinity for the PCP binding site with slightly reduced potency versus PCP but improved metabolic stability.
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 19-60 min | 30-60 min | 1-3 hrs | 2-4 hrs |
| Sublingual | 19-60 min | 30-60 min | 1-3 hrs | 2-4 hrs |
| Insufflated | 4-10 min | 19-40 min | 1-3 hrs | 2-4 hrs |
| Rectal | 10-30 min | 30-60 min | 1-3 hrs | 2-4 hrs |
| Intramuscular | 1-4 min | 10-19 min | 1-3 hrs | 2-4 hrs |
Effect Profile
1 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong dissociative depth and motor impairment with mild insight and mania
Tolerance
Tolerance Decay
Rapid tolerance within a session is commonly reported for PCPโclass dissociatives; crossโtolerance across the class is expected. Estimates above are anecdotal aggregates and vary substantially by individual, dose, and redose pattern.
Cross-Tolerances
Effects
- Physical euphoria
- Stimulation
- Pain relief
- Analgesia
- Numbness
- Loss of balance
- Nausea
- Spontaneous bodily sensations
- Physical disconnection
- Sedation
- Analysis enhancement
- Cognitive euphoria
- Conceptual thinking
- Cognitive disconnection
- Depersonalization
- Amnesia
- Motor control loss
- Derealization
- Memory suppression
- Time distortion
- Tactile enhancement
- Increased music appreciation
- Visual acuity suppression
- Disinhibition
- Derealization
- Tactile suppression
- Spatial disorientation
- Double vision
- Visual disconnection
- Auditory distortion