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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-Cl-MAR

    Aliases: 4c-mar

    Stimulant Research-chemical

    Summary TheDrug.Wiki

    4-Cl-MAR is a novel halogenated aminorex derivative with virtually no human safety data. Halogenated aminorexes may share neurotoxicity concerns seen with halogenated amphetamines. Anecdotal reports suggest inconsistent batch potency and minimal euphoria at doses below 150 mg.

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 30-90 min 1-2 hrs 2-4 hrs 4-6 hrs 6-24 hrs
    Insufflated 5-15 min 20-40 min 2-4 hrs 4-6 hrs 6-24 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.4
    Strong 6/10

    Strong anxiety/jitters and stimulation with moderate focus, mild euphoria

    Stimulation / Energy ×3
    9
    stimulation increased energy wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    5
    euphoria motivation enhancement
    Focus / Productivity ×2
    7
    focus enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding bruxism vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 4-Cl-MAR
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Full tolerance 2d Half tolerance 7d Baseline ~28d

    Model reflects general stimulant patterns and self‑reports; exact kinetics unknown for 4C‑MAR.

    Cross-Tolerances

    other aminorexes
    60%
    amphetamine derivatives
    40%

    Effects TheDrug.Wiki

    Positive
    • Stimulation
    • Increased energy
    Negative
    • Increased heart rate
    • Teeth grinding
    • Insomnia
    • Vasoconstriction
    • Pupil dilation
    • Increased blood pressure
    • Increased perspiration
    • Bruxism
    Positive
    • Focus enhancement
    • Motivation enhancement
    • Euphoria
    • Wakefulness
    • Increased sociability
    • Alertness enhancement
    Negative
    • Anxiety
    • Compulsive redosing
    Neutral
    • Thought acceleration
    • Talkativeness
    Positive
    • Increased libido
    • Increased music appreciation
    • Visual enhancement
    • Tactile enhancement
    Negative
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    • Disinhibition
    • Double vision
    Neutral
    • Dulled perception

    Combinations TripSit

    4-Cl-MAR's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki