Summary
4-CMA is a prodrug that metabolizes to 4-Chloroamphetamine (4-CA), which selectively destroys serotonergic axon terminals. Lasting mood, cognitive and sleep disturbances have been reported after single exposures. Tablets seized in Europe contained 25-150 mg active drug. No recognized medical use exists and quality-control is absent. Strongly discouraged for use due to severe neurotoxic properties.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-15mg | - | - | 60+mg(notrecommended)+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects |
|---|---|---|---|---|
| Oral | 20-60 min | 1-3 hrs | 2-4 hrs | 2-6 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3โ7 days for acute; 1โ3 weeks for full reset
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Temperature regulation suppression
- Teeth grinding
- Increased heart rate
- Insomnia
- Pupil dilation
- Vasoconstriction
- Increased perspiration
- Neurotoxicity symptoms
Positive
- Cognitive euphoria
- Wakefulness
- Mood lift
- Empathy enhancement
- Increased sociability
Negative
- Anxiety
- Motivation suppression
- Thought deceleration
- Depression
- Cognitive fatigue
Positive
- Tactile enhancement
- Increased music appreciation
- Increased libido
- Tracers
- Color enhancement
- Pattern recognition enhancement
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition