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    4-Fluorobutyrfentanyl molecular structure

    4-Fluorobutyrfentanyl Stats & Data

    Pfbf 4-fbf parafluorobutyrfentanyl
    PubChem
    MW368.5
    FormulaC23H29FN2O
    LogP4.5
    IUPACN-(4-fluorophenyl)-N-[1-(2-phenylethyl)piperidin-4-yl]butanamide
    InChIKeyQZFMCYUBPSLOBP-UHFFFAOYSA-N
    Chemical Class Anilidopiperidine
    Psychoactive Class Depressant

    History & Culture

    4-Fluorobutyrfentanyl emerged as a designer drug sold online as part of the broader wave of synthetic opioid analogs appearing in illicit markets. Structurally, it is an analog of butyrfentanyl and is closely related to 4-fluorofentanyl, representing one of numerous modifications to the fentanyl scaffold explored by clandestine chemists. The compound is reportedly rare, and there is limited documentation regarding its origins, synthesis history, or the specific circumstances of its introduction to the recreational drug market. Like many novel synthetic opioids, it appears to have been developed and distributed primarily through online vendors catering to the research chemical market.

    Effect Profile

    Curated + 2 Reports
    Opioid 6.3

    Strong euphoria with moderate itching/nausea, mild pain relief, low sedation

    Euphoria / Warmth×3
    10
    Analgesia×2
    4
    Sedation / Relaxation×1
    3
    Itching / Nausea×1
    7
    Based on reports from:

    Tolerance & Pharmacokinetics

    drugs.wiki

    No tolerance chart. Our decay curves for opioids were estimates, and a curve can make tolerance look longer-lasting than it is, which is the dangerous direction.

    Opioid tolerance drops fast when you stop, and even a few days off can be enough, so a dose that used to be normal can now stop your breathing. Overdose deaths rise sharply after prison, detox or leaving treatment, and tolerance also falls during a hospital stay. After any break, start with a much smaller amount, try a test dose first, don't use alone, and keep naloxone within reach. Alcohol, benzodiazepines, gabapentinoids and other sedatives make an opioid overdose much more likely.

    Sources: FRANK: heroin · National Harm Reduction Coalition · WHO: opioid overdose · Merrall et al. 2010 · Binswanger et al. 2007 · Strang et al. 2003 · FDA 2019: gabapentinoids and breathing

    Experience Report Analysis

    Erowid
    2 Reports
    2015–2015 Date Range
    2 With Age Data

    Demographics

    Gender Distribution

    Too few reports for a chart: gender is known from 2 reports, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?

    • Female 1 of 2
    • Male 1 of 2

    Age Distribution

    Reports Over Time

    Form / Preparation

    Most common forms and preparations, as a share of the 2 reports that give one

    Too few reports for bars: these forms come from 2 reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    • Liquid 2 of 2

    Legal Status

    Country Status Notes
    China Controlled substance Became a controlled substance in October 2015 as part of China's efforts to restrict synthetic opioid production and distribution.
    Sweden Hazardous substance (proposed) Sweden's public health agency recommended classification as a hazardous substance on August 18, 2014. This designation restricts sale and possession under Swedish drug control legislation.
    United States Schedule I Classified as a Schedule I controlled substance under federal law since February 1, 2018. This designation indicates high abuse potential with no accepted medical use.
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