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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-MET

    Aliases: Colour, Metocin, Methylcybin, 4homet, homet, ethocin

    Categories

    Psychedelic Research-chemical
    4-HO-MET structure

    Summary TheDrug.Wiki Erowid

    4-HO-MET is a synthetic tryptamine analogue of psilocin first synthesized by Alexander Shulgin. Often described as more recreational than psilocybin mushrooms due to its lighter headspace and more prominent visual effects with less cognitive intensity. Individual response varies significantly; some users report intense experiences at low doses while others report mild effects at higher doses, possibly due to variations in neurochemistry, metabolism, or batch quality. As a research chemical, long-term health effects remain unknown.

    Perspectives

    “4-HO-MET felt kinda like mushrooms, but without the overwhelming-ness or the destruction of autonomy. Neutered mushrooms—providing psychedelic effects while maintaining greater personal control.”

    “This was still a positive low-end experience, with no real negatives or unwanted side effects. I hope to return to this in due course.”

    Dose Information TheDrug.Wiki PsychonautWiki TripSit

    ROA Light Common Strong Heavy
    Oral 10mg 10-15mg 20mg 20mg+
    Intravenous 5mg 10-15mg 20mg 20mg+
    Smoked 10-25mg 25-35mg 35-60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki PsychonautWiki TripSit

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-40 min 30-60 min 2.0-3.0 hrs 60-90 min 2.0-12.0 hrs 4.0-6.0 hrs
    Insufflated 0-1 min - - - 2.0-8.0 hrs 3.0-7.0 hrs
    Intravenous 1-10 min - 3.0-7.0 hrs - 2.0-8.0 hrs 3.0-7.0 hrs
    Smoked - - - - 2.0-8.0 hrs 25.0-45.0 hrs

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline
    Cross-tolerance
    LSD Psilocybin Psilocin Mescaline DMT 5-MeO-DMT 2C-B 2C-E

    Effects TheDrug.Wiki

    Positive
    • Stimulation
    • Creativity Enhancement
    Negative
    • Nausea
    • Temperature Regulation Suppression
    • Pupil Dilation
    • Increased Heart Rate
    • Increased heart rate
    • Insomnia
    Neutral
    • Spontaneous Bodily Sensations
    • Sedation
    Positive
    • Conceptual Thinking
    • Novelty Enhancement
    • Immersion Enhancement
    • Euphoria
    • Cognitive euphoria
    • Wakefulness
    Negative
    • Anxiety
    Neutral
    • Thought Acceleration
    • Time Distortion
    • Time distortion
    Positive
    • Color Enhancement
    • Pattern Recognition Enhancement
    • Visual Acuity Enhancement
    • Colour Shifting
    • Increased Music Appreciation
    • Synaesthesia
    Negative
    Neutral
    • Changes In Felt Bodily Form
    • Drifting
    • After Images
    • Symmetrical Texture Repetition
    • Internal Hallucination
    • External Hallucination

    Combinations TripSit

    Trip Reports Effect Index

    Wracked with Color nervewing Unity with a Friend Josie My Fourth Experience with Unity Josie Cosmic Copyright Warning Rho Extreme Psychosis Cocoanatta

    PiHKAL / TiHKAL Shulgin

    TiHKAL #21: 4-HO-MET

    Helpful Links

    📘 Experience Reports 📖 PsychonautWiki 📖 TripSit 📖 Bluelight 📖 The Drug Users Bible