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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-HO-PiPT

    Aliases: Piprocin

    Psychedelic Research-chemical

    Summary TheDrug.Wiki

    4-HO-PiPT is a novel substituted tryptamine first identified in 2021 in British Columbia, Canada. It is characterized by an unusually short duration (2-4 hours) compared to most psychedelics, with intense visuals and a heavy bodyload. Users report strong tactile enhancement, significant nausea, confusion, and disorientation during the peak.

    Perspectives

    “4-HO-PiPT was oddly intense in some respects, mild in others. The visual space was an explosion of forms and energy, great iridescent blue ripples with my eyes open and a world of vibrant metallic glowing forms with my eyes closed.”

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 15-30 min 15-30 min 30-60 min 1-2 hrs 1-2 hrs

    Effect Profile

    5 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 4.0
    Moderate 4/10

    Strong body load with moderate visuals, mild headspace

    Visual Intensity ×3
    6
    color enhancement drifting tracers
    Headspace Depth ×3
    4
    introspection time distortion confusion
    Auditory Effects ×1
    0
    ⚠ Body Load / Somatic Effects ×1
    8
    nausea vasoconstriction muscle tension increased heart rate
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 4-HO-PiPT
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Cross-Tolerances

    Psilocin/psilocybin
    70%
    LSD/lysergamides
    50%
    Other 4‑substituted tryptamines (e.g., 4‑HO/4‑AcO‑MET, MiPT, DiPT)
    60%

    Effects Erowid

    Aggregated from 5 Erowid experience reports

    Positive Effects 7

    Euphoria 100.0% 70%
    Tactile Enhancement 100.0% 70%
    Empathy 80.0% 70%
    Stimulation 80.0% 70%
    Introspection 60.0% 70%
    Body High 60.0% 70%
    Color Enhancement 60.0% 70%

    Adverse Effects 2

    Anxiety 60.0% 70%
    Confusion 60.0% 70%

    Combinations TripSit

    4-HO-PiPT's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki