4-HO-PiPT - first trial - threshold I just tested my 4-HO-PiPT with Ehrlich and Froehde, because that's about all that I can think of. It tested as expected, so it's some kind of indole.
4-HO-PiPT
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Piprocin
Summary
4-HO-PiPT is a novel substituted tryptamine first identified in 2021 in British Columbia, Canada. It is characterized by an unusually short duration (2-4 hours) compared to most psychedelics, with intense visuals and a heavy bodyload. Users report strong tactile enhancement, significant nausea, confusion, and disorientation during the peak.
Perspectives
“4-HO-PiPT was oddly intense in some respects, mild in others. The visual space was an explosion of forms and energy, great iridescent blue ripples with my eyes open and a world of vibrant metallic glowing forms with my eyes closed.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-10mg | 10-20mg | 20-30mg | 30mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 15-30 min | 45-90 min | 1.5-2.5 hrs | 2-4 hrs |
Effect Profile
5 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
4.0
Moderate
4/10
Strong body load with moderate visuals, mild headspace
Visual Intensity
×3
6
color enhancement
drifting
tracers
Headspace Depth
×3
4
introspection
time distortion
confusion
Auditory Effects
×1
0
Body Load / Somatic Effects
×1
8
nausea
vasoconstriction
muscle tension
increased heart rate
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use
Reset
7β14 days for baseline
Tolerance Decay
Full tolerance
2d
Half tolerance
7d
Baseline
~10d
Acute tolerance: develops within a single session β the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Acute tachyphylaxis typical of psychedelics develops within the session, with marked shortβterm tolerance for ~24β48 h. By ~1β2 weeks, response approximates baseline. Crossβtolerance across serotonergic psychedelics is expected. Data quality: anecdotal extrapolation from related 4βHO compounds; conservative spacing (β₯14 days) reduces risk of cumulative psychological strain.
Cross-Tolerances
Effects
Aggregated from 5 Erowid experience reports
Positive Effects 7
Euphoria
100.0%
70%
Tactile Enhancement
100.0%
70%
Empathy
80.0%
70%
Stimulation
80.0%
70%
Introspection
60.0%
70%
Body High
60.0%
70%
Color Enhancement
60.0%
70%
Adverse Effects 2
Anxiety
60.0%
70%
Confusion
60.0%
70%
Combinations
Cross-Check 4-HO-PiPT with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 3 reports 3 neutral visit
IΒve been experimenting with 4-HO-PiPT fumarate for about a year now. As it is a relatively new substance, I would like to provide the world some documentation with regards to this chemical. IΒve always procured my supply from the same source.
Piprocin, A Novel Experience A few weeks ago I had tried 20mg piprocin (4-HO-PiPT) and made a post on it in r/obscuredrugs. It was a decent substance, good bodyload, a ton of tactile euphoria but mild visuals.
4-HO-PiPT's nerd page
Pharmacology, chemical data, effect profiles, and more
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