Summary
4-HO-PiPT is a novel substituted tryptamine first identified in 2021 in British Columbia, Canada. It is characterized by an unusually short duration (2-4 hours) compared to most psychedelics, with intense visuals and a heavy bodyload. Users report strong tactile enhancement, significant nausea, confusion, and disorientation during the peak. The compound has very limited human use history and little scientific research. Use harm reduction practices and start with low doses due to steep dose-response curve.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 15-30 min | 15-30 min | 30-60 min | 1-2 hrs | 1-2 hrs |
Tolerance
Build-up
develops rapidly after a single use
Reset
7–14 days for baseline
Cross-tolerance
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Nausea
- Muscle tension
- Increased heart rate
- Insomnia
- Pupil dilation
- Vasoconstriction
- Sedation
- Dilated pupils
Positive
- Euphoria
- Introspection
- Cognitive euphoria
- Wakefulness
Negative
- Confusion
- Memory suppression
- Anxiety
- Compulsive redosing
- Time distortion
- Thought acceleration
Positive
- Color enhancement
- Tracers
- Tactile enhancement
- Increased music appreciation
Negative
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Visual hallucinations
- Drifting