UPDATED TO INCLUDE 2ND TRIP. SEE 3RD COMMENT DOWN! Okay, So I have mentioned before that I have been a moderate prescription opiate user for about 8 years. Never had a reason to jump to heroin or any other harder substance due to being half responsible with my pain clinics and half lucky.
4-MAR
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 4 corroborating sources
- 4 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- dose ladder unverifiable and undisclosed — capped
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 4 corroborating sources
- 4 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Tentative
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- dose ladder unverifiable and undisclosed — capped
Aliases: Ice, U4ea, U4euh, 4-max, Euphoria
Summary
4-MAR exists as cis- and trans-stereoisomers; recreational preparations typically contain racemic cis-4-MAR. Users report clear empathic stimulation with minimal peripheral side effects at moderate doses (10-20 mg), but pronounced vasoconstriction and compulsive redosing at higher doses. Vaporization produces intense rapid onset despite maintaining 6-8 hour duration.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-5mg | 5-10mg | 10-15mg | 15-20mg+ |
| Insufflated | 5-10mg | 10-30mg | 30-50mg | 50mg+ |
| Smoked / Vaporized | 5-10mg | 10-20mg | 30-60mg | 60mg+ |
| Intravenous | 5-10mg | 10-20mg | 20-40mg | 40mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 0.75-2 hrs | 1-2 hrs | 2-4 hrs | 4-10 hrs | 7.75-18 hrs |
| Insufflated | 20-40 min | 30-60 min | 1-3 hrs | 3-6 hrs | 4.83-10.67 hrs |
| Smoked / Vaporized | 0-1 min | 5-15 min | 1-3 hrs | 4-8 hrs | 5.08-11.27 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
5.6
Strong
6/10
Strong anxiety/jitters with moderate stimulation and euphoria, mild focus
Stimulation / Energy
×3
7
stimulation
increased energy
wakefulness
Euphoria / Mood Lift
×2
7
euphoria
cognitive euphoria
motivation enhancement
Focus / Productivity
×2
5
focus enhancement
motivation enhancement
Anxiety / Jitters
×1
10
anxiety
teeth grinding
increased heart rate
bruxism
vasoconstriction
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes 4-MAR, but its built-in data can be thinner than ours. Importing this file adds a separate "4-MAR (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.
⬇ Download import file
Import this file as custom substances
and you get "4-MAR (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer.
Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Tolerance Decay
Full tolerance
1d
Half tolerance
12d
Baseline
~21d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Positive
- Stimulation
- Increased energy
Negative
- Teeth grinding
- Vasoconstriction
- Increased heart rate
- Insomnia
- Pupil dilation
- Increased blood pressure
- Increased perspiration
- Bruxism
Positive
- Euphoria
- Cognitive euphoria
- Motivation enhancement
- Focus enhancement
- Increased sociability
- Empathy enhancement
- Wakefulness
Negative
- Anxiety
- Compulsive redosing
- Talkativeness
Positive
- Increased libido
- Increased music appreciation
- Visual enhancement
- Tactile enhancement
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Disinhibition
- Double vision
- Dulled perception
Combinations
Cross-Check 4-MAR with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Bluelight 8 threads 8 neutral visit
4-methylaminorex - First Time - EUPHORIA!!!! I had heard about Ice (4-methylaminorex) and it caught my attention. It seemed almost too good to be true,and also extremely rare. I had also been interested in methamphetamine so when I found an 'Ice' connection I naturally jumped at the chance.
Kanna ( Sceletium Tortuosum) I reckon this as amongst the top 3 psychoactive plants I think it is better than Kratom no lie. My 3 best psychoactive plants/fungi Marijuana, Magical mushrooms, Kanna Sceletium Tortuosum 0 hour I ate 2-3 grams of my beloved Kanna 'high potency' powder from a good vendor within 15 minutes I...
Ice (4-MAR) - 1st time - Amped & Still Awaiting Comedown 1am - at friend's house. was actually planning on chilling sober and kickin' it. i watch the others go at the crystals. i get ancy and decided ive changed my mind. 115am - paul van dyk on the CD player. place roughly 10mg of 4-MAR on a square of foil.
Some background: It was 2010. I was 21 at the time. I wasn't really into stimulants. I'd had coke a few times, usually in combination with other things. Methamphetamine made me feel jumpy. My skin would tingle and I'd feel as if I was breaking out in cold sweats. Not my thing.
I started out with pot, then e, then before I knew it, I've tried coke, heroin and ice. Out of all that I've tried, I found a great affinity with ice. For so many years of my life, I've always kept to myself & cried alone.
So my cousin (whom I've never talked with because our families have a huge fight going on) met me one day in the theater and we just spoke about our drug life, usual cigs, booze etc.. and then he said he does 'stuff' (slang here for weed) and I was interested.
"ICE" Pills (suspected amps) - Second Time - Reflecting on the "ICE" pills Today I want to reflect on what I believe about the "ICE" speed pills. I used to get these about 1-2 years ago often, and just recently came across some as well.
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