4-Me-NEB
Aliases: Bz-6379, 4-methyl neb
Summary
User reports are highly variable: some batches appear largely inert below 100mg, while others enable prolonged wakefulness (48+ hours) with minimal euphoria but strong goal-directed focus, suggesting functional/ADHD-medication-like properties. Very limited human pharmacology data exists. Detected in Japanese forensic surveys of "dangerous drug" herbal blends.
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral (Extrapolated) | 15-45 min | 30-60 min | 1-2.5 hrs | 2-3 hrs |
| Insufflated (Extrapolated) | 3-10 min | 10-20 min | 1-2.5 hrs | 2-3 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria and anxiety/jitters with moderate stimulation, mild focus
Tolerance
Tolerance Decay
Anecdotal/theoretical: cathinones commonly show rapid within-session tolerance and partial cross‑tolerance across the class, with decay over 1–3 weeks. Avoid multi‑day use. Data quality low; based on mephedrone/NEP user reports and general stimulant patterns.
Cross-Tolerances
Effects
- Stimulation
- Physical euphoria
- Increased heart rate
- Vasoconstriction
- Teeth grinding
- Dry mouth
- Insomnia
- Nausea
- Respiratory depression
- Sedation
- Wakefulness
- Focus enhancement
- Motivation enhancement
- Alertness enhancement
- Cognitive euphoria
- Euphoria
- Anxiety suppression
- Anxiety
- Compulsive redosing
- Talkativeness
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dehydration
- Double vision
- Dulled perception