It is most likely available in larger urban areas, but is quite uncommon. You need to be pretty well connected to get it. Boiling point is very low. You can smoke it by placing about 10 mg on aluminum foil, and holding a lighter under the foil to warm it.
4-METHYLAMINOREX
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- classified Tentative
- classified Research-chemical
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- classified Tentative
- classified Research-chemical
Summary
A very potent stimulant that has quite a long duration of action at around 16 hours.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1-5mg | 5-10mg | 10-15mg | 15mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 5-15 min | 14-18 hrs | 14-18 hrs |
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 4-METHYLAMINOREX there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
⬇ Download import file
Import this file as custom substances
and you get "4-METHYLAMINOREX (Substance Search)" with every
route's full dose ladder and timeline, no typing. Works on iOS and
Android (v15+); the format is confirmed by the app's
developer. The manual values below work for older
versions.
Name
4-METHYLAMINOREX
Unit
mg
Description
4-METHYLAMINOREX Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 1 · light 1-5 · common 5-10 · strong 10-15 · heavy 15+ Oral duration: onset 5-15m · peak 14-18h · total 14-18h · after-effects 1-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 7.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute tolerance; longer for full reset
Tolerance Decay
Full tolerance
2d
Half tolerance
7d
Baseline
~14d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Quantitative tolerance kinetics are not formally characterized in humans; estimates reflect typical stimulant patterns and community observations (tolerance builds over multi‑day binges and partially resolves over 1–3 weeks). Avoid consecutive‑day use to reduce bingeing and sleep deprivation.
Effects
Aggregated from 12 Erowid experience reports
Positive Effects 4
Euphoria
75.0%
70%
Stimulation
50.0%
70%
Empathy
25.0%
70%
Creativity Enhancement
25.0%
70%
Adverse Effects 2
Jaw Clenching
33.3%
70%
Anxiety
25.0%
70%
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 8 reports 5 positive 3 neutral visit
Drug: 4-methylaminorex, aka 'Ice', a member of the oxazoline family Dose: 30 mg orally (at t = 0:00), 30 mg snorted (at t = 1:00) Duration: time to kick in -- 15 min, come up -- 2 hours, plateau -- 3 hours, come down (effects still quite strong) -- 3 hours, come down (effects minimal) -- 3.5 hours TOTAL = 11.5 hours Ex...
I had heard about Ice (4-methylaminorex) and it caught my attention. It seemed almost too good to be true, and also extremely rare. I had also been interested in methamphetamine so when I found an 'Ice' connection I naturally jumped at the chance.
4-methylaminorex experiment: let's clean the house! Time: 10:20 a.m. on a Saturday My household just left for Burning Man, so I want to start off my week of blissful solitude by getting the entire house clean.
I was only able to try 4-MAR once, and obtained from a sysntesis 1.5g of product, yields were much lower then expected. 4-MAR when compared to methamphetamine, in tolerant daily methamphetamine users, took away the desire to use meth during the duration of it's use.
10:10 AM: 20 mgs 4methylaminorex insuf After finishing my morning phone conference, I opened up a gel cap that a friend had brought up for me. It was labeled 20 mgs and I didn't brother to reweigh it.
I was at the social security building getting my food stamp card renewed when an attractive Hispanic chick walks up to me and tell me she wants to parrtay. This happened on the way out of the building so I didn't have an excuse to say no.
I ate about 10 mg of 4-Methylaminorex powder at around 10 AM on a weekday. Did not have a scale. The drug was introduced to me as a study aid, a material good for overcoming writer's block (or other creative blocks), something useful for getting lots of work done, especially intellectual work.
4-METHYLAMINOREX's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 4-METHYLAMINOREX? Let us know. Reports are reviewed by moderators — this is not posted publicly.