4-MPM
Aliases: Pal-747, Bontril, Adipost, Appecon, Melfiat, 4-methylphenmetrazine, mephenmetrazine
Categories
Summary
Phendimetrazine is a phenmetrazine prodrug prescribed for short-term obesity management. It metabolizes into active phenmetrazine, which has known abuse potential but with slower onset than direct administration. Tolerance develops rapidly with regular use. Users should avoid combining with other appetite suppressants or stimulants. Contraindicated in cardiovascular disease, hyperthyroidism, glaucoma, and history of substance abuse.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-15mg | 15-25mg | 25-40mg | 40mg+ |
| Insufflated | 5-10mg | 10-20mg | 20-25mg | 25mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 1-2 hrs | 2-3 hrs | 1-2 hrs |
| Insufflated | 5-15 min | 15-30 min | 1-2 hrs | 2-3 hrs | 1-2 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Stimulation
- Increased energy
- Increased energy/alertness
Negative
- Increased perspiration
- Increased heart rate
- Vasoconstriction
- Teeth grinding
- Insomnia
- Pupil dilation
- Tachycardia
Positive
- Euphoria
- Increased sociability
- Empathy
- Focus enhancement
- Motivation enhancement
- Cognitive euphoria
- Wakefulness
Negative
- Compulsive redosing
- Anxiety
- Time distortion
- Thought acceleration
Positive
- Increased libido
- Increased music appreciation
Negative
- Appetite suppression
- Tinnitus
- Dehydration
- Light sensitivity
- Disinhibition
- Decreased libido
- Increase sexuality
- Visual and audiotory hallucinations itchiness