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    ☠ This substance has been associated with serious adverse events including fatalities. Use extreme caution.
    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4-MTA Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 20 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Aliases: Mta, Flatliners, Golden eagle, 4-methylthioamphetamine

    Summary dose.wiki Erowid TripSit

    4-MTA is an extremely dangerous substance with a high fatality rate. It acts as both a potent serotonin releaser and MAO-A inhibitor, creating severe risk of fatal serotonin syndrome and hyperthermia. The slow onset (30-90 minutes) leads to high redosing risk and accidental overdose.

    Dose Information dose.wiki Drugs.Wiki

    Dose basis. Figures reflect scattered user reports and historical harm-reduction summaries; they are NOT safety guidelines. 4-MTA has a delayed onset and a long, accumulating course; redosing has been repeatedly implicated in severe toxicity. Historic tablets sold as 'ecstasy' in the late 1990s contained 4-MTA and were associated with multiple deaths; misrepresentation remains a risk. Treat any unknown pill/powder as potentially high-dose. Avoid redosing entirely. (Dose figures and this note are from Drugs.Wiki.)

    ROA Light Common Strong Heavy
    Oral 10-20mg 20-30mg 30-40mg 40mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki Drugs.Wiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-90 min 1-2 hrs 2-8 hrs 4-12 hrs 24 hrs 7.5-23.5 hrs

    Effect Profile

    2 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 3.0
    Light+ 3/10

    Moderate body load with mild visuals, low headspace

    Visual Intensity ×3
    5
    color enhancement tracers pattern recognition enhancement
    Headspace Depth ×3
    2
    confusion time distortion
    Auditory Effects ×1
    0
    Body Load / Somatic Effects ×1
    7
    nausea teeth grinding tachycardia increased heart rate
    Empathogen 5.0
    Moderate+ 5/10

    Moderate stimulation and sensory enhancement with mild empathy, low euphoria

    Empathy / Social Openness ×3
    5
    empathy sociability enhancement
    Euphoria / Mood Elevation ×2
    3
    euphoria
    Stimulation ×1
    7
    stimulation wakefulness teeth grinding increased heart rate
    Sensory Enhancement ×1
    7
    tactile enhancement color enhancement increased libido
    Stimulant 3.6
    Moderate 4/10

    Strong anxiety/jitters with mild stimulation and focus, low euphoria

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    3
    euphoria
    Focus / Productivity ×2
    4
    analysis enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety tachycardia increased heart rate teeth grinding
    Based on reports from:

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 4-MTA there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "4-MTA (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    4-MTA
    Unit
    mg
    Description
    4-MTA
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): threshold 5 Β· light 10-20 Β· common 20-30 Β· strong 30-40 Β· heavy 40+
    
    Oral duration: onset 0.5-1.5h Β· come-up 1-2h Β· peak 2-8h Β· offset 4-12h Β· total 7.5-23.5h Β· after-effects 24h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 25 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Half tolerance 3d Baseline ~21d

    Human tolerance kinetics are poorly documented due to rarity and high lethality; assume some acute tolerance with slow recovery over days, and significant pharmacodynamic carryover for at least 24–48 h post-use.

    Effects dose.wiki

    Positive
    • Stimulation
    Negative
    • Nausea
    • Headache
    • Tachycardia
    • Increased heart rate
    • Pupil dilation
    • Teeth grinding
    Neutral
    • Hyperthermia
    • Muscle rigidity
    • Decreased appetite
    Positive
    • Empathy
    • Euphoria
    • Sociability enhancement
    • Wakefulness
    • Analysis enhancement
    Negative
    • Agitation
    • Confusion
    • Anxiety
    Neutral
    • Thought acceleration
    • Time distortion
    Positive
    • Tactile enhancement
    • Increased music appreciation
    • Color enhancement
    • Increased libido
    • Tracers
    • Pattern recognition enhancement
    Negative
    • Light sensitivity
    • Dehydration
    • Appetite suppression
    Neutral
    • Increase sexuality

    Combinations

    Cross-Check 4-MTA with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 2 reports 1 neutral 1 cautionary visit
    Flatlined Beyond Comprehension neutral exp #83154

    The day to end all days it seemed. An experience I was NOT prepared for. Having little money at the time I bought this cheap Flatliner thinking that the media hype surrounding its potential to kill was just well, hype. I WAS WRONG. I take the pill 10+ I am waiting for the pill to kick in.

    jimmywoo
    I Should Have Thought Twice cautionary exp #37909

    [Erowid Note: A substance(s) in this report might be identified incorrectly. Erowid reviewers question the author's identification of the drug described. Although the report is included in the collection, the substance might be something other than the author believed it to be.] I'd rather be addicted to shooting heroi...

    Ice

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