4-MXP
Aliases: Mxp, 2-mxp, Methoxphenidine, Methoxyphenidine, 2-meo-diphenidine
Categories
Summary
Methoxphenidine (commonly called MXP or 2-MXP) is a long-acting dissociative of the diarylethylamine class with particularly extended duration. Oral onset can take 1-2 hours, leading inexperienced users to redose prematurely and experience severe intoxication. Doses above 150 mg have produced severe confusion, blackouts, urinary tract irritation similar to ketamine cystitis, and hospitalizations. Multiple fatalities have been reported with this compound. Large crystals are caustic to nasal tissue; oral capsules are strongly preferred.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50-75mg | 75-120mg | 120-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 0.5-2.0 hrs | 30-60 min | 2.0-5.0 hrs | 2.0-3.0 hrs | 6.0-24.0 hrs | 6.0-8.0 hrs |
| Insufflated | 10-45 min | 15-30 min | 2.0-4.0 hrs | 1.0-2.0 hrs | 6.0-24.0 hrs | 6.0-8.0 hrs |
| Intravenous | 30-60 min | - | 2.0-3.0 hrs | 1.0-2.0 hrs | 6.0-12.0 hrs | 6.0-8.0 hrs |
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Effects
Positive
- Physical euphoria
- Pain relief
- Spontaneous tactile sensations
- Stimulation
Negative
- Clumsiness in movement
- Increased heart rate
- Numbness
- Loss of balance
- Tactile disconnection
- Physical disconnection
Positive
- Cognitive euphoria
- Conceptual thinking
- Euphoria
- Inner calm
- Anxiety suppression
Negative
- Depersonalization
- Derealization
- Motor control loss
- Memory suppression
- Anxiety
- Confusion
- Amnesia
- Dizziness
- Information processing suppression
- Thought deceleration
- Time distortion
- Dissociation
- Altered perception of time
- Astral projection
- Consciousness disconnection
- Perspective alterations
- Perspective distortions
- Physical autonomy
- Thought acceleration
Positive
- Increased music appreciation
- Perception of bodily lightness
Negative
- Spatial disorientation
- Acuity suppression
- Auditory suppression
- Disinhibition
- Double vision
- Frame rate suppression
- Pattern recognition suppression
- Tactile suppression
- Visual disconnection
- Internal hallucinations
- Warm vibration
- Auditory distortion
- Auditory hallucinations
- Autonomous entities
- Environmental cubism
- Environmental orbism
- Perception of decreased weight
- Scenery slicing