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    Ketamine Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 7 corroborating sources
    • 6 ROAs with full dose ladders
    • duration data present
    • 26 combo interactions documented
    • PubChem toxicity data

    Aliases: K, Ket, Jet, Kitty, 2-cxm, kittens

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki drugbank

    Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects.

    Perspectives

    “K is immensely bleak and the K Hole is just one great void. It just feels cold, grey, dull and boring.”

    “Tread carefully.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral BA 17% 50-100mg 100-300mg 300-450mg 450mg+
    Sublingual BA 24-30% 50-100mg 100-300mg 300-450mg 450mg+
    Insufflated BA 45% 10-30mg 30-75mg 75-150mg 150mg+
    Intramuscular BA 93% 10-25mg 25-50mg 50-100mg 100mg+
    Intravenous BA ~100% 5-15mg 15-40mg 40-75mg 75mg+
    Rectal BA 25-30% 50-100mg 100-250mg 250-400mg 400mg+
    Light Common Strong Heavy

    Ketamine Dosing Calculator TripSit NCBI

    Ketamine dosing is weight-dependent — effects vary significantly based on body mass and route of administration. Select your ROA below to see adjusted doses based on its bioavailability.

    via

    Insufflated is the most common recreational route. BA from NCBI NBK470357.

    ⚠️ Doses are adjusted for the selected route based on its bioavailability (NCBI). There is no single "K-Hole dose" — individual sensitivity varies greatly. Always start low and wait.

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 10-30 min 4-19 min 45-90 min 30-60 min 4-8 hrs 1-2 hrs
    Sublingual 4-10 min 4-19 min 30 min 30-60 min 2-12 hrs 1-2 hrs
    Insufflated 4-15 min 4-19 min 30-60 min 30-60 min 2-12 hrs 1-2 hrs
    Intramuscular 1-4 min 4-15 min 15-45 min 30-60 min 2-12 hrs 1-2 hrs
    Intravenous - 1-3 min 3-4 min 30-60 min 2-12 hrs 1-2 hrs
    Rectal 10-19 min 10-19 min 30-40 min 30-60 min 2-12 hrs 1-2 hrs

    Effect Profile

    920 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 712 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 6.9
    Strong+ 7/10

    Strong dissociative depth with moderate insight and motor impairment, low mania

    Dissociative Depth ×3
    8
    depersonalization derealization consciousness disconnection physical disconnection tactile disconnection cognitive disconnection +9 more

    “K is immensely bleak and the K Hole is just one great void.”

    nervewing effectindex

    “I've never gone into a k-hole though so all i can comment is some people have told me they loved it, others they hated it.”

    joe456 bluelight
    Mania / Compulsion ×1
    3
    compulsive redosing disinhibition

    “Still quite dissociative but with a very "on the nose" euphoria.”

    Survived Abortion bluelight

    “It's perhaps a bit better to take MDMA to add stimulation and socialization but MDA makes it a bit more introspective, in addition to adding it's own flavor to the visuals.”

    transitioneer bluelight
    Insight / Novel Thought ×2
    7
    conceptual thinking analysis enhancement subconscious communication perspective alterations unity and interconnectedness personal bias suppression +2 more
    Motor / Sensory Impairment ×1
    7
    motor control loss physical disconnection tactile disconnection tactile suppression spatial disorientation visual disconnection +1 more

    “I feel like I’ve snorted ice, that this icy numbness is radiating from my sinuses outwards.”

    nervewing effectindex

    “You can maintain motor skills on this combo.”

    Survived Abortion bluelight

    User Experience

    dissociative depth “K is immensely bleak and the K Hole is just one great void.” — nervewing, effectindex

    Tolerance

    Build-up develops noticeably with repeated use; chronic use can lead to significant tolerance and bladder damage
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Cross-Tolerances

    Dissociatives

    Effects Erowid Bluelight

    Aggregated from 712 Erowid and 208 Bluelight experience reports

    Positive Effects 58

    Visual Distortions 44.1% 75%
    Music Enhancement 39.2% 83%
    Euphoria 32.7% 84%
    Color Enhancement 32.3% 82%
    Geometric Imagery 32.0% 86%
    Awe 30.0% 82%
    Empathy 29.6% 80%
    Stimulation 27.9% 83%
    Focus Enhancement 25.8% 70%
    Out-Of-Body Experience 24.0% 88%
    Tactile Enhancement 23.4% 80%
    Insight 22.0% 86%
    Closed-Eye Visuals 20.2% 88%
    Mystical Quality 18.0% 85%
    Thought Acceleration 18.0% 79%
    Introspection 16.2% 80%
    Environmental Transfiguration 16.0% 87%
    Sociability Enhancement 14.0% 84%
    Ego Dissolution 13.7% 89%
    Lightness 12.0% 81%

    Adverse Effects 55

    Anxiety 45.7% 83%
    Body Load 34.0% 81%
    Confusion 31.1% 87%
    Fear 28.0% 85%
    Nausea 19.6% 83%
    Sedation 14.5% 80%
    Ataxia 14.0% 84%
    Memory Suppression 12.2% 80%
    Thought Disorganization 12.0% 81%
    Delusion 10.0% 80%
    Body Distortion 10.0% 83%
    Panic 10.0% 83%
    Paranoia 8.0% 78%
    Paranoid Ideation 6.0% 68%
    Communication Suppression 6.0% 80%
    Focus Suppression 6.0% 72%
    Pain Enhancement 6.0% 90%
    Appetite Suppression 6.0% 75%
    Amnesia 6.0% 85%
    Dysphoria 6.0% 85%

    Combinations TripSit

    Cross-Check Ketamine with another substance

    Trip Reports Effect Index

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Reddit 8 reports 2 positive 4 neutral 2 cautionary visit
    I was in love for three hours. positive ▲15 9 comments

    I’ll try to keep this as short as possible but I just needed to share the most beautiful trip I’ve ever had. **Trip intention: To feel romantic love.** I know this sounds weird or even downright pathetic. But I just wanted to know what it felt like. Just once.

    u/LonelyGirlWhoReads · 2023-07-16
    Every-time my friend and I do ketamine together… positive ▲15 1 comments

    My friend and I have done ketamine together three times now. The first time on acid. The second time sober. And this last time on mushrooms. Doing ketamine sober is a mild experience. Maybe we didn’t take enough though. It was pleasant but not anything to write home about.

    u/outershpongle · 2023-01-15
    It felt like death without actually dying. neutral ▲41 11 comments

    Last night I administered 60mg approx of ketamine, IM. Within 5-10 minutes, the effects started to come on strong. I wanted to dance for a bit but the effects were so strong that my legs were numbing out and I lost control of my limbs. so I had to stop.

    u/avalancheheadbangx ★ 2 reports · 2023-08-09
    addicted to the khole (7g in less than a week) neutral r/ketamine ▲18 26 comments

    Used to only consume 1g over the course of a weekend for a festival. But about 3 years ago I started using it at home on the couch and get deeper into the k hole experience. Usage would go up to a gram in a night but still took breaks. Eventually I got up to 3.5g in a weekend.

    u/Active_Blackberry_45 · 2026-04-22
    Most intense and long khole I ever had neutral r/ketamine ▲13 4 comments

    Yesterday, I had the impulse to do a khole dose. But apperently I had really dark coloured rooms that didn't show detailed scenerys. Always dark coloured and blurr. Now, I quit kratom 9 days ago from 30gpd to 0 in two days.

    u/wankwank420 · 2026-05-14
    I think I’m trapped in hell neutral r/ketamine ▲11 11 comments

    tripped so hard that my whole conciouness deconstructed it felt like I was falling through different scenes in a other realm but with a sinister presence to it , it felt like I was being dragged through and eventually I felt the end goal would be to meet the maker himself , it sm...

    u/Impossible-Handle151 ★ 3 reports · 2026-05-05
    I tried ketamine for the first time and damn.. cautionary r/ketamine ▲42 34 comments

    I have experience with lsd,shrooms, excstasy. And almost every other drug except heroin & fentanyl and I took ketamine for the first time 3 days ago and I’ve been doing it daily since. Ketamine really reflects your fears & good sides.

    u/AlternativeLocal8674 · 2026-04-27
    Trying to figure out if I almost died or just an analog cautionary r/ketamine ▲5 22 comments

    I got a oz from a new source. Tried it last weekend at a show and it felt fine at first then all the sudden got hit with this overwhelming feeling of anxiety and raciness and it felt like my whole body was like shutting down, literally had my buddy run to the car and grab narcan...

    u/One_Association_6461 · 2026-04-27
    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    A Decade Plus Love Affair positive exp #113450

    Ketamine is a substance that for better or worse has had a place of some prominence in my life for some time now - it hasn’t been the source of my most profound drug experiences, it’s not the most reliably enjoyable substance, it’s not the most social drug, it’s not even the safest drug - something which is becoming mo...

    Vastness · repeated insufflated
    K Confessions positive exp #2731

    First I'd like to share the more mundane details of my relationship with this substance - the basic logistics of my ketamine usage and its effect on my life. I've been a habitual user of K for over a year and a half, imbibing on an almost daily basis during this time.

    Legofeel · 25 mg IM / 35 mg IM / 50 mg IM
    The Great Light of Enlightenment positive exp #102337

    I am not the best for describing stuff so bear with me. Ketamine is my favourite substance; it is unpredictable, surreal and somewhat life changing with each experience different to its previous one.

    Samuel J · 150-250 mg insufflated
    A Therapy-Oriented Session for Healing neutral exp #107760

    The background to the trip seems undeniably essential to the content of the experience. That said, some of the details of my life are deeply painful, shame-drenched and terrifying to talk about in earnest and despite the anonymity and relative distance afforded by saying these things in a trip report, some of the parti...

    Dankskank · 200 mg insufflated
    First K-hole - The True Horror Behind Reality neutral exp #78894

    Here is a trip report of my first K-hole experience. I had tried quite a few times to reach this level before, but always came up a little short of getting there, though many of those experiences were somewhat profound too. They pale in comparison to this one.

    TryptamineDreamer
    Vacation From Reality neutral exp #105504

    I would say I'm tall, I would not say I'm someone who frequently does drugs, or any type of strong chemical, plants and anything else in that direction for that matter. I'm just an occasional bud burner along with a few experiences with MDMA, LSD, xanax, morphine and a very regretful one with 25i.

    Ringo · repeated insufflated
    Not Particularly Special-K cautionary exp #116342

    A very good friend of mine happens to be heavily addicted to, of all things, Ketamine. We live in a beautiful, up-and-coming, Southeast Asian country where many ultra-high-purity chemicals are produced.

    Fleming · insufflated
    Infinite Ethereal Space cautionary exp #97117

    [Erowid Note: Driving while intoxicated, tripping, or extremely sleep deprived is dangerous and irresponsible because it endangers other people. Don't do it! ] My experience with Ketamine: So I had ordered two gram of ketamine from overseas to my friend and it arrived stealthily packaged in a gameboy cartridge.

    Martin · 2 lines insufflated
    Bluelight 7 threads 2 positive 5 neutral visit
    Ketamine Retrospective Multiple Experiences Over 12 Years positive

    Ketamine is a substance that for better or worse has had a place of some prominence in my life for some time now - it hasn’t been the source of my most profound drug experiences, it’s not the most reliably enjoyable substance, it’s not the most social drug, it’s not even the safest drug - something which is becoming mo...

    scraped 2026-03-14
    Iv K Series Experienced Chapter 1 Look Out For The Hole positive

    The reason I love IV K so much is because it's so outstandingly surreal, it feels like an ENTIRELY different drug than when done orally, intranasally, rectally, or IMed. Hell, I personally never liked ketamine until I started shooting it. And once I did--it was the most incredible rush... I was in love.

    scraped 2026-03-14
    Ketamine In India Nepal And Thailand Real World Trip Report The Sequel neutral

    well here is the sequel i promised to my 'Ketamine in Mexico' report found both here and on the web at http://ketamex.tripod.com ...enjoy... Hmmmmm....hello all....well Mexico was fun and all, but I felt it was time to explore brave new worlds or whatever.

    scraped 2026-03-14
    Ketamine Experienced Stuck In The Hole And Cant Get Out neutral

    Hey all, This isn't so much a report of any specific trip, more an account of a long period of exposure to ketamine. I had my first line of ketamine about four years ago when I was 16, I still remember it vividly now. It was a dose so small that I would wipe it off the table without any regret nowadays.

    scraped 2026-03-14
    Ketamine 1 Gram Very Experienced The Border Between K Hole And Narcosis neutral

    This is an older trip report of mine; the experience happened in the spring of 2011 which is also when I wrote the report. It was written in dutch though and I figured it is probably interesting enough to translate to english for international availability.

    scraped 2026-03-14
    Homeless In Japan With A Fuckload Of Drugs Day 3 By Kandy neutral

    This is by a certain little Asain American girl most of us know/love/hate. It is not about harm reduction nor do I condone or approve of here actions. -spun Continuation of Homeless in Japan with a FUCKLOAD of Drugs. Day 1. 5-MeO-DPT. By Kandy K.

    scraped 2026-03-14
    Ketamine Intermediate User A Single Consciousness neutral

    i've tried ketamine a few times before, but most of the times it was just one of a multiplicity of powders to go up my nose, and thus i was never able to isolate the effects of the ketamine amongst the effects of the others.

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    Dissociatives Big & Dandy Ketamine Thread 4: I was filled with the Holey Spirit

    The Big & Dandy Ketamine thread iupac = (RS)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone External Information Links: Wikipedia Ketamine page Erowid Ketamine vault Erowid Ketamine FAQ "The Ketamine Konundrum" FAQ: The Beginners Guide to Ketamine Subthreads: First Time Dosage and Methods of Administration Oral Admini...

    Read full thread on Bluelight →

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