Ketamine
Aliases: K, Ket, Jet, Kitty, 2-cxm, kittens
Summary
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects.
Perspectives
“K is immensely bleak and the K Hole is just one great void. It just feels cold, grey, dull and boring.”
“Tread carefully.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral BA 17% | 50-100mg | 100-300mg | 300-450mg | 450mg+ |
| Sublingual BA 24-30% | 50-100mg | 100-300mg | 300-450mg | 450mg+ |
| Insufflated BA 45% | 10-30mg | 30-75mg | 75-150mg | 150mg+ |
| Intramuscular BA 93% | 10-25mg | 25-50mg | 50-100mg | 100mg+ |
| Intravenous BA ~100% | 5-15mg | 15-40mg | 40-75mg | 75mg+ |
| Rectal BA 25-30% | 50-100mg | 100-250mg | 250-400mg | 400mg+ |
Ketamine Dosing Calculator
Ketamine dosing is weight-dependent — effects vary significantly based on body mass and route of administration. Select your ROA below to see adjusted doses based on its bioavailability.
Insufflated is the most common recreational route. BA from NCBI NBK470357.
⚠️ Doses are adjusted for the selected route based on its bioavailability (NCBI). There is no single "K-Hole dose" — individual sensitivity varies greatly. Always start low and wait.
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 10-30 min | 4-19 min | 45-90 min | 30-60 min | 1-2 hrs |
| Sublingual | 4-10 min | 4-19 min | 30 min | 30-60 min | 1-2 hrs |
| Insufflated | 4-15 min | 4-19 min | 30-60 min | 30-60 min | 1-2 hrs |
| Intramuscular | 1-4 min | 4-15 min | 15-45 min | 30-60 min | 1-2 hrs |
| Rectal | 10-19 min | 10-19 min | 30-40 min | 30-60 min | 1-2 hrs |
Effect Profile
920 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 712 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong dissociative depth with moderate insight and motor impairment, low mania
“K is immensely bleak and the K Hole is just one great void.”
“I've never gone into a k-hole though so all i can comment is some people have told me they loved it, others they hated it.”
“Still quite dissociative but with a very "on the nose" euphoria.”
“It's perhaps a bit better to take MDMA to add stimulation and socialization but MDA makes it a bit more introspective, in addition to adding it's own flavor to the visuals.”
“I feel like I’ve snorted ice, that this icy numbness is radiating from my sinuses outwards.”
“You can maintain motor skills on this combo.”
User Experience
Tolerance
Tolerance Decay
Cross-Tolerances
Effects
Aggregated from 712 Erowid and 208 Bluelight experience reports