4Cl-iBF - Substance Search

Summary TheDrug.Wiki

Potency of 4Cl-iBF is not precisely established but in vitro binding suggests it is weaker than fentanyl yet far more potent than morphine - DO NOT eyeball powder; use a calibrated 0.1 mg (100 ug) scale or volumetric solution. Numerous post-mortem and seized-sample reports confirm involvement in fatal overdoses; naloxone reverses toxicity but may require repeated dosing because of longer half-life than naloxone. Strong histamine release and chest-wall rigidity have been described with analogous compounds.

Dose Information TheDrug.Wiki

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki

ROA	Onset	Peak	Offset	After Effects
Insufflated	2-5 min	15-45 min	1-2 hrs	2-6 hrs
Sublingual	5-15 min	15-45 min	1-2 hrs	2-6 hrs

Effect Profile

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Opioid 7.0

Strong+ 7/10

Strong euphoria, itching/nausea, and pain relief with low sedation

Euphoria / Warmth ×3

10

physical euphoria euphoria cognitive euphoria warmth mood lift

Analgesia ×2

8

analgesia pain relief

Sedation / Relaxation ×1

3

sedation

⚠ Itching / Nausea ×1

10

itching nausea constipation

Based on reports from:

Erowid Experience Reports PsychonautWiki 4Cl-iBF

Tolerance

Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance

Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

Tolerance Decay

Full tolerance 3d Half tolerance 7d Baseline ~21d

Opioid tolerance develops rapidly with frequent use and decays slowly over weeks. Exact timelines vary considerably; conservative spacing between sessions is strongly advised. Data are largely extrapolated from clinical opioid literature and community reports, not controlled studies on 4Cl‑iBF.