Summary
4F-4-MAR first appeared in Slovenia (2018) and was forensically confirmed via HR-MS and NMR. The para-fluoro substitution raises lipophilicity and slows oxidative metabolism, explaining >16 hour subjective duration. User reports highlight pronounced anorexia, clean but long-lasting stimulation and muted euphoria compared to classic 4-MAR. Oral dosing is markedly more effective than nasal; vaporization yields harsh pyrolysis products and is strongly discouraged. As with all aminorex derivatives, pulmonary arterial hypertension remains a serious long-term risk—regular echocardiograms are advised for frequent users.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 15-45 min | 30-90 min | 2-6 hrs | 6-10 hrs | 6-24 hrs |
| Insufflated | 5-15 min | 15-45 min | 2-6 hrs | 6-10 hrs | 6-24 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Stimulation
- Increased energy
Negative
- Increased heart rate
- Vasoconstriction
- Bruxism
- Insomnia
- Teeth grinding
- Increased blood pressure
- Pupil dilation
- Increased perspiration
Positive
- Focus enhancement
- Motivation enhancement
- Euphoria
- Alertness enhancement
- Wakefulness
- Increased sociability
Negative
- Anxiety
- Compulsive redosing
- Talkativeness
- Thought acceleration
Positive
- Increased libido
- Increased music appreciation
- Visual enhancement
- Tactile enhancement
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Disinhibition
- Double vision
- Dulled perception