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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4F-4-MAR

    Aliases: 4-fpo, 4f-mar, Pf-4-mar

    Stimulant Research-chemical

    Summary TheDrug.Wiki

    4F-4-MAR first appeared in Slovenia (2018) and was forensically confirmed via HR-MS and NMR. The para-fluoro substitution raises lipophilicity and slows oxidative metabolism, explaining >16 hour subjective duration. User reports highlight pronounced anorexia, clean but long-lasting stimulation and muted euphoria compared to classic 4-MAR.

    Dose Information TheDrug.Wiki

    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Comeup Peak Offset After Effects
    Oral 15-45 min 30-90 min 2-6 hrs 6-10 hrs 6-24 hrs
    Insufflated 5-15 min 15-45 min 2-6 hrs 6-10 hrs 6-24 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.4
    Strong 6/10

    Strong anxiety/jitters and stimulation with moderate focus, mild euphoria

    Stimulation / Energy ×3
    9
    stimulation increased energy wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    5
    euphoria motivation enhancement
    Focus / Productivity ×2
    7
    focus enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate bruxism teeth grinding vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 4F-4-MAR
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 12d Baseline ~21d

    Effects TheDrug.Wiki

    Positive
    • Stimulation
    • Increased energy
    Negative
    • Increased heart rate
    • Vasoconstriction
    • Bruxism
    • Insomnia
    • Teeth grinding
    • Increased blood pressure
    • Pupil dilation
    • Increased perspiration
    Positive
    • Focus enhancement
    • Motivation enhancement
    • Euphoria
    • Alertness enhancement
    • Wakefulness
    • Increased sociability
    Negative
    • Anxiety
    • Compulsive redosing
    Neutral
    • Talkativeness
    • Thought acceleration
    Positive
    • Increased libido
    • Increased music appreciation
    • Visual enhancement
    • Tactile enhancement
    Negative
    • Appetite suppression
    • Light sensitivity
    • Dehydration
    • Disinhibition
    • Double vision
    Neutral
    • Dulled perception

    Combinations TripSit

    4F-4-MAR's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki