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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    4F-4-MAR Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • duration data present
    • 18 combo interactions documented
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Aliases: 4-fpo, 4f-mar, Pf-4-mar

    Summary dose.wiki

    4F-4-MAR first appeared in Slovenia (2018) and was forensically confirmed via HR-MS and NMR. The para-fluoro substitution raises lipophilicity and slows oxidative metabolism, explaining >16 hour subjective duration. User reports highlight pronounced anorexia, clean but long-lasting stimulation and muted euphoria compared to classic 4-MAR.

    Dose Information dose.wiki

    ROA Threshold
    Oral 5mg
    Insufflated 15mg

    Only a threshold dose is documented for this substance โ€” the smallest amount with a noticeable effect. There is no published light/common/strong ladder to show above it.

    Onset, Duration & After-effects dose.wiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 15-45 min 30-90 min 2-6 hrs 6-10 hrs 6-24 hrs 8.75-18.25 hrs
    Insufflated 5-15 min 15-45 min 2-6 hrs 6-10 hrs 6-24 hrs 8.33-17 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.4
    Strong 6/10

    Strong anxiety/jitters and stimulation with moderate focus, mild euphoria

    Stimulation / Energy ×3
    9
    stimulation increased energy wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    5
    euphoria motivation enhancement
    Focus / Productivity ×2
    7
    focus enhancement motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety increased heart rate bruxism teeth grinding vasoconstriction

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track 4F-4-MAR there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    4F-4-MAR
    Unit
    mg
    Description
    4F-4-MAR
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): threshold 5
    Insufflated dose (mg): threshold 15
    
    Oral duration: onset 15-45m ยท come-up 0.5-1.5h ยท peak 2-6h ยท offset 6-10h ยท total 8.75-18.25h ยท after-effects 6-24h
    Insufflated duration: onset 5-15m ยท come-up 15-45m ยท peak 2-6h ยท offset 6-10h ยท total 8.33-17h ยท after-effects 6-24h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3โ€“7 days for acute; 1โ€“3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 12d Baseline ~21d

    Effects dose.wiki

    Positive
    • Stimulation
    • Increased energy
    Negative
    • Increased heart rate
    • Vasoconstriction
    • Bruxism
    • Insomnia
    • Teeth grinding
    • Increased blood pressure
    • Pupil dilation
    • Increased perspiration
    Positive
    • Focus enhancement
    • Motivation enhancement
    • Euphoria
    • Alertness enhancement
    • Wakefulness
    • Increased sociability
    Negative
    • Anxiety
    • Compulsive redosing
    Neutral
    • Talkativeness
    • Thought acceleration
    Positive
    • Increased libido
    • Increased music appreciation
    • Visual enhancement
    • Tactile enhancement
    Negative
    • Appetite suppression
    • Light sensitivity
    • Dehydration
    • Disinhibition
    • Double vision
    Neutral
    • Dulled perception

    Combinations

    Cross-Check 4F-4-MAR with another substance

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