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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    5-APDB

    Psychedelic Stimulant Empathogen Research-chemical

    Summary TripSit

    An entactogenic amphetamine stimulant with similar structure and effects to MDMA. An analogue of MDA, it is a highly selective serotonin releaser but inhibits reuptake of serotonin (weakly), dopamine and norepinephrine.

    Perspectives

    “A worthy addition to the toolkit. Perhaps its most interesting feature is its total lack of stimulation. It is psychedelic too, at least mentally.”

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 50-75mg 75-125mg - 125-200mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak Total
    Oral 19-60 min 4-8 hrs 4-8 hrs

    Effect Profile

    2 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 2.8
    Light+ 3/10

    Mild visuals with low body load and headspace

    Visual Intensity ×3
    4
    color enhancement tracers
    Headspace Depth ×3
    1
    time distortion
    Auditory Effects ×1
    0
    ⚠ Body Load / Somatic Effects ×1
    3
    sweating increased heart rate
    Empathogen 4.1
    Moderate 4/10

    Moderate sensory enhancement and stimulation with mild euphoria, low empathy

    Empathy / Social Openness ×3
    2
    increased sociability
    Euphoria / Mood Elevation ×2
    5
    euphoria mood lift
    Stimulation ×1
    6
    stimulation wakefulness increased heart rate
    Sensory Enhancement ×1
    7
    tactile enhancement color enhancement increased libido
    Stimulant 4.0
    Moderate 4/10

    Moderate anxiety/jitters with mild stimulation and euphoria, low focus

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    5
    euphoria mood lift
    Focus / Productivity ×2
    2
    thought acceleration
    ⚠ Anxiety / Jitters ×1
    7
    anxiety increased heart rate sweating
    Based on reports from:
    Effect Index I Am a Big Gushing Fool Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki 5-APDB
    View methodology →

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7–14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects TripSit

    Positive
    • Increased energy/alertness
    • Stimulation
    Negative
    • Weight loss
    • Sweating
    • Increased heart rate
    • Pupil dilation
    Neutral
    • Decreased need for sleep
    • Decreased appetite
    • Distrubed sleep patterns
    • Bruxia
    Positive
    • Euphoria
    • Increased sociability
    • Mood lift
    • Wakefulness
    Negative
    • Agressiveness
    • Anxiety
    Neutral
    • Excessive talking
    • Moodiness
    • Thought acceleration
    • Time distortion
    Positive
    • Tactile enhancement
    • Increased music appreciation
    • Color enhancement
    • Increased libido
    • Tracers
    Negative
    • Light sensitivity
    • Dehydration
    • Appetite suppression
    Neutral
    • Increase sexuality
    • Visual and audiotory hallucinations itchiness

    Combinations TripSit

    Trip Reports Effect Index

    I Am a Big Gushing Fool nervewing
    5-APDB's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 Bluelight 📖 PsychonautWiki