5-Cl-AMT
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- no dose data
- duration data present
- 19 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 1 source
- no dose data
- duration data present
- 19 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Pal-542
Summary
5-Cl-AMT (5-chloro-ฮฑ-methyltryptamine; PAL-542) combines three properties with harm-reduction implications: it is a serotonin-dopamine releasing agent, a potent 5-HT2A agonist, and an in vitro MAO-A inhibitor. Treat it as an MAOI during the session window even though clinical reversibility is not established. Start with a microtest of 0.5-1 mg to gauge sensitivity; community trials report activity at 1-2 mg and full days' worth of effects from 8-12 mg.
Dose Information
No curated dose ladder is available for this substance. The figures below are drawn from SubstanceIndex (DoseWiki) as a fallback — often a conservative threshold only. Treat them as approximate and cross-reference before use.
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 30-90 min | 1-2 hrs | 4-8 hrs | 4-8 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Mild body load and visuals with low headspace
Moderate stimulation and sensory enhancement with mild empathy, low euphoria
Strong anxiety/jitters with moderate stimulation, mild euphoria, low focus
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Pupil dilation
- Mild tremor or jaw tension
- Nystagmus
- Increased heart rate
- Teeth grinding
- Vasoconstriction
- Insomnia
- Increased perspiration
- Increased body temperature
- Entactogenic warmth and sociability
- Alertness enhancement
- Euphoria
- Wakefulness
- Motivation enhancement
- Increased sociability
- Anxiety
- Time distortion
- Talkativeness
- Thought acceleration
- Color enhancement
- Increased music appreciation
- Tactile enhancement
- Increased libido
- Tracers
- Light sensitivity
- Dehydration
- Appetite suppression
- Disinhibition
- Spontaneous physical sensations
Combinations
Cross-Check 5-Cl-AMT with another substanceHelpful Links
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