5-DBFPV Stats & Data
CCCC(N1CCCC1)C(=O)c1ccc2OCCc2c1CIGWUZUBQBQZAO-UHFFFAOYSA-NReceptor Profile
Receptor Actions
Effect Profile
CuratedStrong anxiety/jitters and focus with moderate euphoria, mild stimulation
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Tolerance builds rapidly with binge/redose patterns typical of pyrrolidinophenones and decays over 1–3 weeks of abstinence. Cross‑tolerance within the α‑PVP/MDPV family is probable based on similar mechanisms (NDRI). Data quality is largely anecdotal; model values are approximations.
Cross-Tolerances
Legal Status
| Country | Status | Notes |
|---|---|---|
| Sweden | 5-DBFPV is illegal |
Harm Reduction
drugs.wiki• Potency is in the low-to-tens of milligrams; an accurate 0.001 g scale and a 1–2 mg allergy test substantially reduce overdose risk. Compared with many cathinones, pyrrolidinophenones like MDPV/α‑PVP active at similar ranges have produced severe adverse reactions at small mis-measurements. • Expect powerful reinforcement: reports with 5‑DBFPV/analogues describe strong 'fiending' and compulsive redosing; pre-portion doses and set a hard session limit before starting to reduce escalation. • Cardiovascular strain and vasoconstriction (cold extremities, headache, chest pressure) are common with this class; stop use if chest pain, severe headache, or shortness of breath occurs and seek urgent care. • Insufflation can worsen local vasoconstriction and cause significant nasal irritation; oral dosing is generally less compulsive and less harsh on mucosa. • Vaporizing/smoking produces a near‑instant onset that can markedly increase craving and redose frequency; this also spikes heart rate and blood pressure, so conservative testing or avoiding this ROA is prudent. • Injection of synthetic cathinones carries high risks (tissue damage, infections, rapid tolerance, severe psychosis); avoid IV/IM use. • Sleep deprivation strongly amplifies anxiety, paranoia and psychosis risks with pyrrolidinophenones; plan for adequate sleep and avoid multi‑day use. • Avoid combinations with MAOIs, tramadol, bupropion, or other stimulants; these mixtures are associated with hypertensive events, seizures, and toxic CNS overstimulation. • Caffeine, nicotine and synthetic cannabinoids can add to cardiovascular stress; keep caffeine low and avoid novel cannabinoids on stimulant days. • Drug checking: mislabeling within the cathinone market is common (e.g., α‑PVP sold as '3‑MMC'); reagent tests may be weak/ambiguous—use lab checking where available and titrate doses cautiously from very low if untested. • Even where checking is available, lab methods have limits (e.g., ~0.1% detection thresholds); trace adulterants may be missed—assume unknowns and proceed cautiously. • Hydration: sip small amounts of water regularly; avoid heavy alcohol, which increases dehydration and masks stimulant strain. • For anxious comedowns, small, pre‑planned doses of a prescribed benzodiazepine may help, but avoid stacking with alcohol, opioids, or Z‑hypnotics due to respiratory depression risk. • Do not drive or operate machinery while under acute effects or during the residual stimulation/insomnia window. • Individuals with cardiovascular disease, uncontrolled hypertension, seizure disorders, or a history of stimulant‑induced psychosis are at elevated risk and should avoid this compound.
References
Data Sources
Cited References
- Bluelight: discussion thread - 5-DBFPV (benzofuran analogue of α-PVP)
- EMCDDA: Risk Assessment - α-PVP (comparative cathinone data)
- Forensic Toxicology - Recently abused synthetic cathinones, α-pyrrolidinophenone derivatives
- MDPI Molecules - Synthetic Cathinones: Recent Developments and Enantioselectivity
- PsychonautWiki: List of Substances (5-DBFPV listed)
- TripSit: /DeDgrl aggregate sheet – onset & after-effects
- Reddit: 500 mg insufflated binge case report
- Reddit: first-experience report (oral 5-DBFPV)
- Cerilliant certified reference solution announcement
- MDPI Molecules review – cathinone SAR & abuse liability
- LC-QTOF-MS identification paper (forensic case work)
- DEA Microgram Journal 2016 – seizures list
- Virginia DFS Toxicology Procedures Manual – analytical parameters
Drugs.wiki References
- SubstanceSearch: 5‑DBFPV (timings)
- Erowid: MDPV Effects & Duration (compulsion, timelines)
- Erowid: α‑PVP Vault (class background)
- Bluelight: 5‑DBFPV thread (user potency/duration reports)
- Reddit: 5‑DBFPV first‑experience (ROA, effects)
- TripSit: Drug combinations (MAOIs, stimulants, tramadol, caffeine)
- Erowid: Bupropion (seizure risk, NDRI)
- EMCDDA/EUDA: Synthetic cathinones—Injection risks
- Saferparty: α‑PVP sold as 3‑MMC (mislabel warnings)
- Drug Checking Community: Service & technology limitations (LOD ~0.1%)
- Drugs‑Forum: Vasoconstriction overview
- PubChem: 5‑DBFPV hydrochloride entry