T+1hr - First signs are noted, light headed, quite floaty, slight pupil dilation. T+1hr30mins - Much more pronounced but effects are still strengthening. Reminiscent of Adderall but less speedy and more euphoric. Also reminds me of 6-APB come up. T+2hr - Definite plateau in effects reached.
5-IT
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 3 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Research-chemical
Aliases: 5-api, 5-2-it
Summary
An empathogenic stimulant with a very long duration, prone to cause overheating and potentially quite dangerous. Related to ฮฑMT, though described as being less psychedelic and with much stronger stimulating effects.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 50mg | 50-100mg | 100-150mg | 150mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 1.5-2 hrs | 8-12 hrs | 8-12 hrs |
Effect Profile
4 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
2.8
Light+
3/10
Mild visuals with low body load and headspace
Visual Intensity
×3
4
color enhancement
tracers
Headspace Depth
×3
1
time distortion
Auditory Effects
×1
0
Body Load / Somatic Effects
×1
3
sweating
increased heart rate
Empathogen
4.1
Moderate
4/10
Moderate sensory enhancement and stimulation with mild euphoria, low empathy
Empathy / Social Openness
×3
2
increased sociability
Euphoria / Mood Elevation
×2
5
euphoria
mood lift
Stimulation
×1
6
stimulation
wakefulness
increased heart rate
Sensory Enhancement
×1
7
tactile enhancement
color enhancement
increased libido
Stimulant
4.0
Moderate
4/10
Moderate anxiety/jitters with mild stimulation and euphoria, low focus
Stimulation / Energy
×3
5
stimulation
wakefulness
Euphoria / Mood Lift
×2
5
euphoria
mood lift
Focus / Productivity
×2
2
thought acceleration
Anxiety / Jitters
×1
7
anxiety
increased heart rate
sweating
Based on reports from:
Tolerance
Build-up
develops rapidly after a single use
Reset
7โ14 days for baseline
Tolerance Decay
Full tolerance
1h
Half tolerance
10d
Baseline
~14d
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 4 Erowid experience reports
Positive Effects 2
Euphoria
75.0%
70%
Music Enhancement
75.0%
70%
Adverse Effects 0
Combinations
Cross-Check 5-IT with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 4 reports 4 neutral visit
15:00 - 50mg 5-IT orally (same as I do with aMT) 15:30 - Feeling a lot of tingles and rushes. Zero nausea. 16:00 - Feeling good, and some euphoria, so listen to music which sounds great. 17:00 - Coming down, which his left me rather disappointed as it was far too quick and light for me compared with aMT.
I bought it from a reputable source, who gave me also an indication on the dose to use for research (50mg). I put 50-60 mg in a glass with orange juice, the taste is not so bad. I was a little tired when I took the 5-IT but after 15 mins the tiredness passed.
20mg (weighed on a 0.000 scale) gave me what can only be described as, a dirtier AMT like experience, but with less visuals. The body load is pretty large on this one, with Shulgin's reports of increased heart rate and etc being correct.
5-IT's nerd page
Pharmacology, chemical data, effect profiles, and more
→
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 5-IT? Let us know. Reports are reviewed by moderators — this is not posted publicly.