5-MeO-DPT - Substance Search

Summary TheDrug.Wiki TripSit

5-MeO-DPT is a Schedule I controlled substance in the United States as a positional isomer of 5-MeO-DiPT, and is also controlled in many other jurisdictions. Its psychedelic effects are described as ambiguous and physically uncomfortable by most users, with minimal visual component and strong auditory distortions. Set and setting are critical; avoid operating vehicles or machinery.

Perspectives

“I typically do not find myself drawn to the 5-MeO tryptamines, though they have plenty of merit. I came into this experience expecting a burdensome trial but was pleasantly surprised by both the gentleness and emotional depth this compound presented.”

— Nervewing, nervewing.blogspot.com 18 mg oral

Dose Information TheDrug.Wiki TripSit

ROA	Light	Common	Strong	Heavy
Oral	3mg	3-5mg	5-10mg	10mg+

Light Common Strong Heavy

Onset, Duration & After-effects TheDrug.Wiki TripSit

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Oral	20-60 min	30-60 min	1-2 hrs	1-2 hrs	1-3 hrs	2.8-6 hrs

Effect Profile

8 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Psychedelic 5.6

Strong 6/10

Moderate visuals with mild headspace and auditory effects, low body load

Visual Intensity ×3

7

color enhancement drifting tracers brightened colour

Headspace Depth ×3

4

emotion enhancement time distortion confusion

Auditory Effects ×1

4

auditory distortion

⚠ Body Load / Somatic Effects ×1

2

muscle tension

Based on reports from:

Erowid Experience Reports PsychonautWiki 5-MeO-DPT

Tolerance

Build-up develops rapidly after a single use (serotonergic psychedelic)

Reset 7–14 days for baseline

Tolerance Decay

Full tolerance 2d Half tolerance 7d Baseline ~14d

Pattern inferred from broader serotonergic psychedelic use: noticeable tolerance if re‑used within 24–72 h; ~1–2 weeks commonly restores much of sensitivity; 2–3 weeks usually returns to baseline. Data quality: anecdotal/community consensus rather than controlled studies.