5-Methylethylone
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- classified Research-chemical
Aliases: 5-me, 5-methyl-ethylone, 5-methyl-bk-mdea
Summary
Also known as 5-methyl ethylone or 5-ME, this is a cathinone drug and analogue of ethylone. Little is known about this obscure compound but it is reasonable to assume it has an effect profile similar to other stimulants of the cathionone class, with a slightly higher potency than ethylone. Potentially entactogenic and a monoamine releasing agent.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 30-60mg | 60-150mg | 150-300mg | 300mg+ |
| Oral | 50-100mg | 100-250mg | 250-400mg | 400mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Insufflated | 1-10 min | 2-3 hrs |
| Oral | 20-40 min | 2-4 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria with moderate anxiety/jitters, mild stimulation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track 5-Methylethylone there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
5-Methylethylone Source: SubstanceSearch (substancesearch.com) Insufflated dose (mg): light 30-60 · common 60-150 · strong 150-300 · heavy 300+ Oral dose (mg): light 50-100 · common 100-250 · strong 250-400 · heavy 400+ Insufflated duration: onset 1-10m · peak 2-3h Oral duration: onset 20-40m · peak 2-4h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 105 mg (Insufflated).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Increased energy/alertness
- Stimulation
- Weight loss
- Sweating
- Increased heart rate
- Nausea
- Decreased need for sleep
- Decreased appetite
- Distrubed sleep patterns
- Bruxia
- Euphoria
- Increased sociability
- Mood lift
- Wakefulness
- Cognitive euphoria
- Agressiveness
- Anxiety
- Excessive talking
- Moodiness
- Time distortion
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Increased libido
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Increase sexuality
- Visual and audiotory hallucinations itchiness
Combinations
Cross-Check 5-Methylethylone with another substanceHelpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for 5-Methylethylone? Let us know. Reports are reviewed by moderators — this is not posted publicly.