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    5F-AKB48 molecular structure

    5F-AKB48 Stats & Data

    5f-apinaca 5fapinaca 5fakb48
    NPS DataHub
    MW383.51
    FormulaC23H30FN3O
    CAS1400742-13-3
    IUPACN-(1-adamantyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide
    SMILESFCCCCCn1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2ccccc12
    InChIKeyUCMFSGVIEPXYIV-UHFFFAOYSA-N
    Cannabinoids; 2020/2.1 Von Indol Pyrazol und 4-Chinolon abgeleitete Verbindungen; 2021/2.1 Von Indol Pyrazol und 4-Chinolon abgeleitete Verbindungen; 2022/2.1 Von Indol Pyrazol und 4-Chinolon abgeleitete Verbindungen
    Chemical Class Cannabinoid

    Subjective Effects

    Physical
    • Spontaneous tactile sensations: The body high of 5F-AKB-48 can be described as a sharp, uncomfortable, all-encompassing, electric tingling sensation that spreads over the body after initial ingestion. It maintains a consistent presence that quickly rises with the onset and hits its limit once the peak has been reached before immediately dissipating.
    • Motor control loss: This substance causes a partial to moderate suppression of motor control which intensifies proportional to dose, but rarely results in a complete inability to walk and perform basic movements.
    • Appetite enhancement: As with many other cannabinoids, 5F-AKB-48 causes an increase in appetite, known colloquially as "the munchies" in popular American and United Kingdom culture. Clinical studies and survey data have found that cannabis increases food enjoyment and interest in food. This is thought to be due to the way in which endocannabinoids in the hypothalamus activate cannabinoid receptors that are responsible for maintaining food intake.
    • Pain relief: Cannabinoids have been clinically demonstrated to provide pain relief via agonism of cannabinoid receptors CB1 and CB2, which extends to synthetic cannabinoid receptor agonists.
    • Perception of increased weight or Perception of decreased weight
    • Changes in gravity
    • Dehydration: This is known colloquially as "cotton mouth" in popular American and United Kingdom culture.
    • Vasodilation
    Cognitive
    • Anxiety: In comparison to other cannabinoids, this compound is particularly prone to inducing feelings of anxiety and it should therefore be avoided by people who are particularly prone to this state of mind.
    • Paranoia
    • Current mind state enhancement
    • Thought connectivity
    • Thought deceleration
    • Conceptual thinking
    • Mindfulness
    • Information processing suppression
    • Dream suppression
    Sensory
    Auditory
    • Enhancements

    Forked from Subjective Effect Documentation work by Josie Kins, September 2015. Via dose.wiki (CC0).

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational 5F-AKB48 use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because 5F-AKB48 has very little history of human usage. Anecdotal evidence from people who have tried 5F-AKB48 within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). Informal experiments have shown that overdose will cause physical discomfort including heart palpitations, vertigo and sedation at much lower than dangerous doses, usually causing the user to suffer large amounts of anxiety or to fall asleep.

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 3d Half tolerance 21d Baseline ~28d

    Experience Report Analysis

    Erowid
    4 Reports
    2012–2016 Date Range
    4 With Age Data

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Real-World Dose Distribution

    62K Doses

    From 2 individual dose entries

    Form / Preparation

    Most common forms and preparations reported

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