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    8-Chlorotheophylline

    Stimulant

    Summary PsychonautWiki

    8-Chlorotheophylline (1,3-dimethyl-8-chloroxanthine or 8-CTP) is a stimulant drug of the xanthine class that is closely related to caffeine in both its chemical structure and effects. It is mainly used as a wakefulness-promoting agent found within dimenhydrinate, where it counteracts the drowsiness effects present with diphenhydramine. 8-Chlorotheophylline can cause heart problems in people who take large doses of dimenhydrinate as both of the active ingredients in the drug, Diphenhydramine, and 8-Chlorotheophylline together can cause severe tachycardia.

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 6.0
    Strong 6/10

    Strong focus and anxiety/jitters with moderate stimulation, mild euphoria

    Stimulation / Energy ×3
    6
    stimulation wakefulness alertness enhancement
    Euphoria / Mood Lift ×2
    5
    physical euphoria motivation enhancement
    Focus / Productivity ×2
    10
    focus enhancement analysis enhancement memory enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety jitteriness increased heart rate teeth grinding
    Based on reports from:
    Erowid Experience Reports PsychonautWiki 8-Chlorotheophylline
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects

    Positive
    • Stimulation
    • Bronchodilation
    • Physical euphoria
    Negative
    • Increased heart rate
    • Increased blood pressure
    • Nausea
    • Increased perspiration
    • Jitteriness
    • Teeth grinding
    Neutral
    • Frequent urination
    Positive
    • Alertness enhancement
    • Wakefulness
    • Focus enhancement
    • Motivation enhancement
    • Analysis enhancement
    • Memory enhancement
    Negative
    • Anxiety
    • Irritability
    Neutral
    • Talkativeness
    • Thought acceleration
    Positive
    • Increased libido
    • Tactile enhancement
    • Increased Music Appreciation
    • Increased Libido
    • Increased music appreciation
    Negative
    • Light sensitivity
    • Appetite suppression
    • Appetite Suppression
    • Dehydration
    • Disinhibition
    8-Chlorotheophylline's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 PsychonautWiki