9-Me-BC
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: 9-methyl-norharman
Summary
Rodent and cell data show 9-Me-BC up-regulates tyrosine hydroxylase and BDNF, promotes neurite outgrowth, and reverses rotenone/MPTP dopaminergic injury. IC50 โ1 ยตM (MAO-A) and 15 ยตM (MAO-B) imply mild dietary tyramine sensitivity. Users report subtle but clean motivation, pattern-recognition boost, and mood brightening; bitterness limits sublingual dwell time.
Dose Information
Dose basis. Human dosing is not established in clinical literature; values below are aggregated from community reports and should be treated as anecdotal. Start at the low end due to possible MAO-A/B inhibition and interindividual sensitivity. Anecdotal ROA. Users frequently report marked bitterness and transient mucosal burning/numbness; avoid prolonged mucosal contact if irritation occurs. Consider diluting in PEG-400/ethanol rather than DMSO to reduce sting. Do not use if you have oral lesions. (Dose figures and this note are from Drugs.Wiki.)
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-10mg | 10-25mg | 25-40mg | 40mg+ |
| Sublingual | 2-10mg | 10-25mg | 25-35mg | 35mg+ |
| Insufflated | 1-5mg | 5-15mg | 15-25mg | 25mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-90 min | 2-4 hrs | 3-6 hrs | 5.5-11.5 hrs |
| Sublingual | 10-30 min | 2-4 hrs | 3-6 hrs | 5.17-10.5 hrs |
| Insufflated | 5-15 min | 2-4 hrs | 3-6 hrs | 5.08-10.25 hrs |
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9-Me-BC Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 5 ยท light 5-10 ยท common 10-25 ยท strong 25-40 ยท heavy 40+ Sublingual dose (mg): threshold 2 ยท light 2-10 ยท common 10-25 ยท strong 25-35 ยท heavy 35+ Insufflated dose (mg): threshold 1 ยท light 1-5 ยท common 5-15 ยท strong 15-25 ยท heavy 25+ Oral duration: onset 0.5-1.5h ยท peak 2-4h ยท offset 3-6h ยท total 5.5-11.5h ยท after-effects 12-24h Sublingual duration: onset 10-30m ยท peak 2-4h ยท offset 3-6h ยท total 5.17-10.5h ยท after-effects 12-24h Insufflated duration: onset 5-15m ยท peak 2-4h ยท offset 3-6h ยท total 5.08-10.25h ยท after-effects 12-24h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 17.5 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Tolerance pattern is inferred from community cycles and MAOI-class experience; no formal human data. Anecdotally, consecutive heavy dosing for a week can blunt effects; spacing doses and cycling (โค14 days on, โฅ14 off) is commonly used to mitigate this.
Cross-Tolerances
Effects
- Clean Mental Energy
- Reduced Stimulant Tolerance
- Mental/physical stimulation
- Nausea
- Physical discomfort
- Pupil dilation
- Restlessness
- Sweating/chills
- Decreased appetite
- Increased Motivation
- Enhanced Working Memory
- Mild Euphoria
- Introspection
- Anxiety
- Appetite Suppression
- Photophobia
- Sexual Side-effects
- Spontaneous physical sensations
Combinations
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