AEM
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- descriptive-only dose data
- 19 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 1 source
- descriptive-only dose data
- 19 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Ξ-ethylmescaline, Ξ-ethyl-3,4,5-trimethoxyphenethylamine
Summary
AEM is an extremely rare and poorly documented phenethylamine psychedelic first synthesized by Alexander Shulgin and described in PiHKAL as entry #1. Shulgin reported that doses exceeding 220 mg produced few to no psychoactive effects, classifying it as essentially inactive. The compound's inactivity discouraged Shulgin from synthesizing further alpha-position-extended mescaline analogues (such as alpha-propylmescaline or alpha-butylmescaline).
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | Unknown(inactive) | - | - | - |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Low visuals and headspace
Tolerance
Tolerance Decay
No established activity; tolerance patterns cannot be inferred for AEM itself. If the ingested material is actually an active serotonergic psychedelic, expect typical crossβtolerance with other psychedelics lasting days to weeks.
Effects
- Dilated pupils
- Introspection
- No significant psychoactive effects reported
- Color enhancement
- Visual distortions
Combinations
Cross-Check AEM with another substancePiHKAL / TiHKAL
Helpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for AEM? Let us know. Reports are reviewed by moderators — this is not posted publicly.