AEM
Aliases: ฮ-ethylmescaline, ฮ-ethyl-3,4,5-trimethoxyphenethylamine
Summary
AEM is an extremely rare and poorly documented phenethylamine psychedelic first synthesized by Alexander Shulgin and described in PiHKAL as entry #1. Shulgin reported that doses exceeding 220 mg produced few to no psychoactive effects, classifying it as essentially inactive. The compound's inactivity discouraged Shulgin from synthesizing further alpha-position-extended mescaline analogues (such as alpha-propylmescaline or alpha-butylmescaline).
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | Unknown(inactive)mg | - | - | - |
Light
Common
Strong
Heavy
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Psychedelic
3.1
Light+
3/10
Low visuals and headspace
Visual Intensity
×3
3
color enhancement
visual distortions
Headspace Depth
×3
2
introspection
Auditory Effects
×1
0
Body Load / Somatic Effects
×1
0
Based on reports from:
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7โ14 days for partial reset; full reset may take weeks โ tolerance loss greatly increases overdose risk
Effects
Neutral
- Dilated pupils
Positive
- Introspection
- No significant psychoactive effects reported
Positive
- Color enhancement
- Visual distortions
Combinations
PiHKAL / TiHKAL
AEM's nerd page
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