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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    AEM

    Aliases: ฮ‘-ethylmescaline, ฮ‘-ethyl-3,4,5-trimethoxyphenethylamine

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    Summary TheDrug.Wiki

    AEM is an extremely rare and poorly documented phenethylamine psychedelic first synthesized by Alexander Shulgin and described in PiHKAL as entry #1. Shulgin reported that doses exceeding 220 mg produced few to no psychoactive effects, classifying it as essentially inactive. The compound's inactivity discouraged Shulgin from synthesizing further alpha-position-extended mescaline analogues (such as alpha-propylmescaline or alpha-butylmescaline). Research in rodents suggests these extended homologues are non-hallucinogenic. Due to the complete lack of human psychoactive data and unknown safety profile, AEM should be considered an inactive research chemical with no established use case.

    Dose Information TheDrug.Wiki

    ROA Light Common Strong Heavy
    Oral Unknown(inactive)mg - - -
    Light Common Strong Heavy

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7โ€“14 days for partial reset; full reset may take weeks โ€” tolerance loss greatly increases overdose risk

    Effects TheDrug.Wiki

    Neutral
    • Dilated pupils
    Positive
    • Introspection
    Negative
    Neutral
    • No significant psychoactive effects reported
    Positive
    • Color enhancement
    Negative
    Neutral
    • Visual distortions

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #1: AEM

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