Summary
Opioid analgesic that is selective for the ฮผ-opioid receptor. It has around 80% the potency of Morphine when taken orally.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-10mg | 10-25mg | 25mg | 25mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | After Effects |
|---|---|---|---|
| Oral | 15-45 min | 6.0-8.0 hrs | 1.0-6.0 hrs |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7โ14 days for partial reset; full reset may take weeks โ tolerance loss greatly increases overdose risk
Effects
Positive
- Analgesia
- Stimulation
- Physical euphoria
Negative
- Dry Mouth
- Increased heart rate
- Nausea
- Itchiness
- Relaxant
- Pupil constriction
- Sedation
Positive
- Euphoria
- Mood lift
- Reduced anxiety
- Cognitive euphoria
- Anxiety suppression
Negative
- Constipation
- Compulsive redosing
- Anxiety
- Thought deceleration
- Time distortion
Positive
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
Negative
- Disinhibition
- Light sensitivity
- Appetite suppression
- Dehydration
- Double vision
- Dulled perception