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    Alpha-GPC Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present

    Aliases: Alfa-gpc, Choline alfoscerate, L-alpha glycerylphosphorylcholine

    Nootropic

    Summary dose.wiki PsychonautWiki

    Alpha-GPC is legal as a dietary supplement in the US and Canada but is a prescription medication in some European countries. A 2021 study found increased stroke risk with long-term use (10+ years), so extended daily use may warrant caution. Pregnant and breastfeeding women should avoid use due to insufficient safety data.

    Dose Information dose.wiki PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 100-300mg 300-500mg 500-1000mg 1000mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects dose.wiki PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 45-75 min 1-2 hrs 2-4 hrs 6 hrs 3.75-7.25 hrs

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes Alpha-GPC, but its built-in data can be thinner than ours. Importing this file adds a separate "Alpha-GPC (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "Alpha-GPC (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up after prolonged and repeated usage
    Reset 14 days

    Effects dose.wiki PsychonautWiki

    Positive
    • Subtle Stimulation
    • Stamina Enhancement
    • Stimulation
    Negative
    • Headaches
    • Fatigue
    • Headache
    • Teeth grinding
    Neutral
    • Gastrointestinal Distress
    • Body odor alteration
    • Stamina intensification
    Positive
    • Focus Enhancement
    • Memory Enhancement
    • Motivation Enhancement
    • Wakefulness
    • Dream Potentiation
    • Mindfulness
    • Thought Connectivity
    • Anxiety Suppression
    • Addiction Suppression
    Neutral
    • Focus intensification
    Positive
    • Bodily Control Enhancement
    • Visual Acuity Enhancement
    • Acuity Enhancement
    • Auditory Acuity Enhancement
    • Color Enhancement
    Negative
    • Light sensitivity
    • Appetite Suppression
    • Dehydration
    Neutral
    • Olfactory Intensification
    Alpha-GPC's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki