Home
    Disclaimer
    ← Back to AM-1248
    AM-1248 molecular structure

    AM-1248 Stats & Data

    Psychedelic Research-chemical Cannabinoid
    NPS DataHub
    MW390.57
    FormulaC26H34N2O
    CAS335160-66-2
    IUPAC1-[(N-methylpiperidin-2-yl)methyl]-3-(adamant-1-oyl)indole
    SMILESCN1CCCCC1Cn1cc(C(=O)C23CC4CC(CC(C4)C2)C3)c2ccccc12
    InChIKeyJRECAXBHMULNJQ-UHFFFAOYSA-N
    2020/2.1 Von Indol Pyrazol und 4-Chinolon abgeleitete Verbindungen; 2021/2.1 Von Indol Pyrazol und 4-Chinolon abgeleitete Verbindungen; 2022/2.1 Von Indol Pyrazol und 4-Chinolon abgeleitete Verbindungen
    Chemical Class Cannabinoid
    Psychoactive Class Psychedelic
    Half-Life Unknown in humans; effects are short‑lived when inhaled, suggesting rapid distribution/elimination; detection and PK data for AM‑1248 specifically are scarce in open literature.

    Effect Profile

    Curated
    Psychedelic 5.6

    Strong visuals with mild body load, headspace, and auditory effects

    Visual Intensity×3
    8
    Headspace Depth×3
    4
    Auditory Effects×1
    4
    Body Load / Somatic Effects×1
    5
    Based on reports from:
    Erowid Experience Reports PsychonautWiki AM-1248

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Unknown in humans; effects are short‑lived when inhaled, suggesting rapid distribution/elimination; detection and PK data for AM‑1248 specifically are scarce in open literature.
    Addiction Potential
    Moderate to high. Synthetic cannabinoids show rapid tolerance development and a recognized withdrawal syndrome (sleep disturbance, irritability, anxiety, nausea; occasionally seizures), particularly with daily/frequent use.

    Tolerance Decay

    Full tolerance 3d Half tolerance 14d Baseline ~28d

    Tolerance and cross‑tolerance patterns are inferred from user surveys and clinical observations of SCRAs as a class; quantitative values are illustrative to help plan spacing between sessions and should not be treated as precise pharmacometrics.

    Cross-Tolerances

    Cannabis (THC)
    50% ●○○
    Other synthetic cannabinoids
    70% ●○○

    Harm Reduction

    drugs.wiki

    Evidence-backed harm-reduction points and rationale added below in this message. See citations. Ki/affinity values for AM‑1248 vary by source; secondary compilations suggest nanomolar CB binding with CB2 > CB1 selectivity, but primary in vitro data are limited in open sources accessible here. Treat potency as very high and batch-variable.

    References

    Drugs.wiki References

    ← Back to AM-1248