AMB-FUBINACA
Aliases: Amb
Summary
AMB-FUBINACA is among the most potent synthetic cannabinoids known (CB1 K i β0.9 nM). A few milligrams can dose hundreds of people; weighing with a scale no better than 1 mg is unsafeβvolumetric or pre-dilution onto inert herb is essential. Responsible for >50 fatalities in New Zealand (2017β2019) and the 2016 βzombieβ outbreak in Brooklyn, USA.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset |
|---|---|---|---|
| Smoked | 1 min | 5-25 min | 30-90 min |
| Oral | 15-45 min | 30-90 min | 30-90 min |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
3.4
Light+
3/10
Strong euphoria with low sedation
Anxiolysis
×3
0
Sedation / Relaxation
×2
3
sedation
Motor / Cognitive Impairment
×1
0
Euphoria / Mood Lift
×1
8
euphoria
physical euphoria
Based on reports from:
Tolerance
Build-up
develops over 1β4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Tolerance Decay
Full tolerance
3d
Half tolerance
37d
Baseline
~60d
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Tac tachycardia / palpitations
- Dry mouth
- Nausea / projectile vomiting
- Seizures at high/unknown doses
- Nausea
- Increased heart rate
- Muscle rigidity or catatonia
- Sedation
Positive
- Euphoria
Negative
- Profound short-term memory suppression
- Severe anxiety / panic
- Confusion and dissociation
- Hallucinations, paranoia
- Anxiety
- Intense, rapid cannabis-like intoxication
- Euphoria or dysphoria switching rapidly
- Time dilation
- Time distortion
Positive
- Tracers
- Color enhancement
- Tactile enhancement
- Increased music appreciation
- Enhanced tactile sensation
- Pattern recognition enhancement
- Closed-eye visuals at higher doses
- Dulled perception
- Drifting
- Auditory distortion
Combinations
AMB-FUBINACA's nerd page
Pharmacology, chemical data, effect profiles, and more
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