Summary
Amineptine is an atypical tricyclic antidepressant and central nervous system stimulant. It is an indirect dopamine agonist, with additional stimulation of the adrenergic system. Its antidepressant effects are similar to other tricyclic antidepressants but it has a more rapid action, is better tolerated and has little cardiovascular, analgesic or anorectic effects.
Tolerance
Build-up
develops rapidly after a single use (serotonergic psychedelic)
Reset
7–14 days for baseline
Effects
Positive
- Muscle relaxation
- Physical euphoria
- Anxiolytic
Negative
- Motor impairment
- Respiratory depression
- Nausea
- Sedation
- Itchiness
- Sedative
- Dystaxia
Positive
- Reduced anxiety
- Anxiety suppression
- Cognitive euphoria
- Euphoria
Negative
- Dizziness
- Amnesia
- Motor control loss
- Thought deceleration
- Compulsive redosing
- Constipation
Positive
- Increased music appreciation
- Increased libido
Negative
- Disinhibition
- Appetite suppression
- Double vision
- Dehydration
- Light sensitivity
- Dulled perception
- Internal hallucination
- Internal hallucinations