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    Disclaimer
    ☠ This substance has been associated with serious adverse events including fatalities. Use extreme caution.
    ⚠ Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Bezitramide Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 19 combo interactions documented
    • dose data not in PW/TripSit (unverifiable)

    Aliases: R-4845, Burgodin

    Depressant Opioid

    Summary TheDrug.Wiki

    Withdrawn from Dutch market in 2004 following pediatric fatality. Extremely delayed onset encourages dangerous redosing before peak effects manifest. Historical 5 mg tablets represented supratherapeutic doses for opioid-naive users.

    Dose Information TheDrug.Wiki

    ROA Light Common Strong Heavy
    Oral 0.5-1mg 1-2.5mg 2.5-5mg 5mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki

    ROA Onset Peak Offset After Effects Total
    Oral 0.5-3.5 hrs 2.5-5 hrs 8-12 hrs 6-12 hrs 12-24 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 6.4
    Strong 6/10

    Strong euphoria with moderate itching/nausea, mild pain relief, low sedation

    Euphoria / Warmth ×3
    10
    physical euphoria cognitive euphoria euphoria warmth
    Analgesia ×2
    4
    pain relief
    Sedation / Relaxation ×1
    3
    sedation
    ⚠ Itching / Nausea ×1
    6
    nausea constipation
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Bezitramide
    View methodology →

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 6d Half tolerance 14d Baseline ~35d

    Opioid tolerance builds rapidly with daily use and decays over weeks after cessation; cross‑tolerance is expected with other μ‑opioid agonists. Quantitative values are approximate and based on general opioid patterns rather than bezitramide‑specific trials; interpret cautiously.

    Effects TheDrug.Wiki

    Positive
    • Pain relief
    • Physical euphoria
    • Cough suppression
    • Stimulation
    Negative
    • Respiratory depression
    • Nausea
    • Tachycardia
    Neutral
    • Sedation
    • Itchiness
    • Difficulty urinating
    Positive
    • Cognitive euphoria
    • Anxiety suppression
    • Reduced anxiety
    • Wakefulness
    • Motivation enhancement
    • Euphoria
    • Alertness enhancement
    Negative
    • Constipation
    • Anxiety
    Neutral
    • Talkativeness
    Positive
    • Warmth
    • Increased music appreciation
    • Increased libido
    Negative
    • Appetite suppression
    • Light sensitivity
    • Disinhibition
    • Dehydration
    Neutral
    • Dulled perception
    • Internal hallucination
    • Warm flush

    Combinations TripSit

    Cross-Check Bezitramide with another substance

    Bezitramide's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    💊 Pill Identifier 📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki