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    Bromo-DragonFLY molecular structure

    Bromo-DragonFLY Stats & Data

    Abdf B-dfly Dragonfly Bromo-d-fly Dob-dragonfly bdfly bromo-dragon-fly
    NPS DataHub
    MW294.15
    FormulaC13H12BrNO2
    CAS502759-67-3
    IUPAC1-(4-bromofuro[2,3-f][1]benzoxol-8-yl)propan-2-amine
    SMILESCC(N)Cc1c2ccoc2c(Br)c2ccoc12
    InChIKeyGIKPTWKWYXCBEC-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Amphetamine
    Psychoactive Class Psychedelic / Stimulant

    Receptor Profile

    Receptor Actions

    Agonists
    5-HT2A receptor agonist (full)
    5-HT2B receptor agonist (full)
    5-HT2C receptor agonist (full)
    Inhibitors
    Monoamine oxidase-A inhibitor (potent)

    Receptor Binding

    5-HT 2 agonist

    History & Culture

    1990s–1998

    Bromo-DragonFLY emerged from academic research conducted at Purdue University during the mid-1990s, where it was initially developed as a novel chemical tool for studying serotonin receptor binding in rat brain tissue. The compound was formally synthesized and characterized in 1998 by Matthew Parker, who derived it from the structurally related DOB-FLY. That same year, the substance was first described in the scientific literature by David E. Nichols and colleagues, establishing its pharmacological profile and extreme potency relative to other phenethylamine psychedelics.

    2005–2010

    Following nearly a decade of existence solely within academic contexts, Bromo-DragonFLY transitioned into human experimental psychoactive markets in May 2005 when quantities of the compound became commercially available. By 2006, it had been encountered as a novel designer drug, marking its first documented appearance in recreational contexts. The substance briefly gained popularity within research chemical communities around 2010, though this period of availability would prove short-lived due to the serious incidents that followed.

    2007–2011

    The extreme potency and prolonged duration of Bromo-DragonFLY contributed to several severe adverse events that significantly impacted its availability and legal status. In September 2007, a 35-year-old Swedish man suffered catastrophic tissue necrosis following a massive overdose of unknown quantity, ultimately requiring amputation of the front portion of his feet and several fingers due to the compound's severe vasoconstrictive effects. A particularly consequential incident occurred in October 2009 when laboratory testing confirmed that a batch of Bromo-DragonFLY had been distributed mislabeled as 2C-B-FLY, a structurally related compound approximately twenty times less potent by weight. This labeling error is believed to have contributed to multiple lethal overdoses and additional hospitalizations as users inadvertently consumed doses far exceeding safe thresholds. On May 7, 2011, two young adults in the United States died and several others required hospitalization after overdosing on Bromo-DragonFLY that they believed was 2C-E. These fatal incidents, stemming largely from misidentification and mislabeling rather than informed use, led to the substance's prohibition in multiple jurisdictions and its rapid disappearance from research chemical markets.

    Effect Profile

    Curated + 45 Reports
    Psychedelic 8.5

    Strong visuals, headspace, body load, and auditory effects

    Visual Intensity×3
    1010
    Headspace Depth×3
    107.8
    Auditory Effects×1
    810
    Body Load / Somatic Effects×1
    107.1
    Catalog Erowid
    Stimulant 6.8

    Strong stimulation and anxiety/jitters with moderate euphoria and focus

    Stimulation / Energy×3
    109.6
    Euphoria / Mood Lift×2
    65.3
    Focus / Productivity×2
    64.9
    Anxiety / Jitters×1
    109.1
    Catalog Erowid

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1d Half tolerance 12d Baseline ~21d

    Experience Report Analysis

    Erowid
    45 Reports
    2004–2012 Date Range
    17 With Age Data
    27 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 45 experience reports (45 Erowid)

    45 Reports
    27 Effects Detected
    9 Positive
    9 Adverse
    9 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 9

    Stimulation 55.6% 70%
    Color Enhancement 44.4% 70%
    Euphoria 35.6% 70%
    Music Enhancement 35.6% 70%
    Tactile Enhancement 31.1% 70%
    Empathy 28.9% 70%
    Focus Enhancement 24.4% 70%
    Introspection 22.2% 70%
    Body High 17.8% 70%

    Adverse Effects 9

    Anxiety 42.2% 70%
    Confusion 31.1% 70%
    Nausea 15.6% 70%
    Muscle Tension 13.3% 70%
    Sweating 13.3% 70%
    Headache 11.1% 70%
    Pupil Dilation 8.9% 70%
    Psychosis 8.9% 70%
    Jaw Clenching 6.7% 70%

    Dosage Distribution

    Dose distribution from experience reports

    Median: 600.0 µg IQR: 250.0–1000.0 µg n=11

    Real-World Dose Distribution

    62K Doses

    From 46 individual dose entries

    Oral (n=22)

    Median: 0.5mg 25th: 0.25mg 75th: 0.94mg 90th: 1.05mg
    mg/kg median: 0.005 mg/kg 75th: 0.012

    Form / Preparation

    Most common forms and preparations reported

    Body-Weight Dosing

    Dose relative to body weight from reports with weight data

    Median: 0.008 mg/kg IQR: 0.003–0.025 mg/kg n=11

    Redose Patterns

    Redosing behavior across 30 reports

    23.3% Redosed
    1.3 Avg Doses
    120m Median Interval

    Legal Status

    Not scheduled under the UN Convention on Psychotropic Substances 1971
    Country Status Notes
    Australia Schedule 9 (Prohibited) Listed under Schedule 9 of the Poisons Standard nationally since February 2009, making possession, production, and sale illegal. Additionally added to Schedule 2 of the Queensland Drugs Misuse Regulation 1987 as of September 9, 2011.
    Canada Schedule III (CDSA) Added to Schedule III of the Controlled Drugs and Substances Act on October 12, 2016, under the broad classification of '2C-phenethylamines and their salts, derivatives, isomers and salts of derivatives and isomers' which encompasses compounds with a 2,5-dimethoxyphenethylamine core.
    Denmark Illegal (Narcotic) Banned on December 3, 2007, following recommendations from the Danish Health Ministry. Classified as a dangerous narcotic substance, prohibiting possession, manufacture, importation, supply, and usage.
    Finland Illegal Classified as an illegal designer drug as of March 12, 2012. Added to the national list of controlled substances.
    Germany Controlled (NpSG) Controlled under the Neue-psychoaktive-Stoffe-Gesetz (New Psychoactive Substances Act) as a derivative of 2-phenethylamine. Production and sale are prohibited; however, possession and import are not penalized when intended solely for personal consumption.
    Japan Controlled Designated as a controlled substance effective August 19, 2015.
    Norway Narcotic Listed on the Norwegian narcotics list and controlled under the 'Derivatbestemmelsen,' an analogue act-type provision that regulates structurally similar compounds.
    Poland Uncontrolled Not currently scheduled or controlled under Polish drug legislation.
    Romania Illegal Added as an illegal substance under Law 143/2000 on February 10, 2010. Possession, production, and sale are prohibited.
    Sweden Schedule IV (Narcotic) Listed as a Schedule IV narcotic substance as of January 3, 2008, under Medical Products Agency regulation LVFS 2007:14. Previously classified as a 'health hazard' on July 15, 2007, under SFS 2007:600, which prohibited sale, purchase, retail, and possession.
    Switzerland Likely Illegal (Uncertain) Legal status remains ambiguous. May potentially fall under Verzeichnis E point 130 or Buchstabe C of controlled substances regulations due to structural relationships with controlled amphetamine derivatives, though the exact scope of these definitions is unclear.
    Turkey Illegal Classified as a controlled drug. Possession, production, supply, and importation are prohibited.
    United Kingdom Psychoactive Substances Act 2016 / Class A (Unclear) Not explicitly named in the Misuse of Drugs Act 1971. Coverage under the phenylethylamine Class A catch-all clause is disputed due to its benzodifuran structure. Definitively covered by the Psychoactive Substances Act 2016 when sold or traded for human consumption.
    United States Unscheduled (Federal) / Schedule I (Oklahoma) Not scheduled at the federal level. The Federal Analogue Act may apply if sold for human consumption due to structural similarities with DOB and 2C-B. Listed as a Schedule I controlled substance in the state of Oklahoma.
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