Buphedrone
Summary
A cathinone stimulant first discovered in 1928, has gained some modest popularity as a mephedrone replacement. Said to be to be around 2-3x more potent than methcathinone.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-30mg | 30-50mg | - | 50-80mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Oral | 10-20 min | 2-3 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
3.8
Moderate
4/10
Strong anxiety/jitters and euphoria with mild stimulation
Stimulation / Energy
×3
4
stimulation
alertness enhancement
Euphoria / Mood Lift
×2
9
physical euphoria
cognitive euphoria
euphoria
Focus / Productivity
×2
0
Anxiety / Jitters
×1
10
anxiety
increased heart rate
teeth grinding
vasoconstriction
Based on reports from:
Tolerance
Build-up
develops rapidly, often within a single session; compulsive redosing common
Reset
a few days for acute tolerance
Tolerance Decay
Full tolerance
1h
Half tolerance
4d
Baseline
~5d
Effects
Positive
- Stimulation
- Physical euphoria
- Muscle relaxation
Negative
- Increased heart rate
- Nausea
- Respiratory depression
- Vasoconstriction
- Motor impairment
- Teeth grinding
- Sedation
Positive
- Alertness enhancement
- Cognitive euphoria
- Euphoria
- Anxiety suppression
- Reduced anxiety
Negative
- Compulsive redosing
- Anxiety
- Thought deceleration
- Talkativeness
- Time distortion
Positive
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
Negative
- Light sensitivity
- Disinhibition
- Dehydration
- Appetite suppression
- Double vision
- Dulled perception
Combinations
Buphedrone's nerd page
Pharmacology, chemical data, effect profiles, and more
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