CBDA
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 16 combo interactions documented
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 16 combo interactions documented
- dose data not in PW/TripSit (unverifiable)
Summary
CBDA is the raw acidic precursor of CBD found in fresh cannabis and hemp plants. Heating above 110°C rapidly converts it to CBD via decarboxylation, so CBDA products must remain unheated to preserve potency. In vitro and animal research shows CBDA has approximately 100-fold greater affinity for the 5-HT1A serotonin receptor compared to CBD and exhibits selective COX-2 enzyme inhibition.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 5-10mg | 10-30mg | 30-60mg | 60mg+ |
| Sublingual | 2-6mg | 6-20mg | 20-40mg | 40mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 15-45 min | 1-3 hrs | 1-2 hrs | 4-8 hrs |
| Sublingual | 15-45 min | 1-3 hrs | 1-2 hrs | 4-8 hrs |
Tolerance
Tolerance Decay
No controlled data. Repeated daily use appears to show minimal escalation needs anecdotally; any tolerance seems to be modest and reverses within 2–4 weeks off use.
Cross-Tolerances
Effects
- Nausea suppression
- Pain relief
- Muscle relaxation
- Inflammation reduction
- Anxiety suppression
- Mood uplift
- Clear-headedness
- Cognitive enhancement
- Non-intoxicating
Combinations
Cross-Check CBDA with another substanceHelpful Links
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