CBDV
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 16 combo interactions documented
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- 16 combo interactions documented
- dose data not in PW/TripSit (unverifiable)
Aliases: Gwp42006, Cannabidivarol
Summary
Clinical studies using doses up to 800 mg twice daily for 8 weeks have shown good safety with mostly mild gastrointestinal upset and somnolence. Like CBD, CBDV is a moderate inhibitor of several CYP450 enzymes; use caution with narrow-therapeutic-index drugs. Early evidence suggests anticonvulsant, anti-inflammatory and possible nootropic or attention-enhancing properties.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-50mg | 50-200mg | 200-400mg | 400mg+ |
| Smoked | 2-5mg | 5-15mg | 15-30mg | 30mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 0.5-2 hrs | 2-4 hrs | 2-3 hrs | 6-8 hrs |
| Smoked | - | 2-4 hrs | 2-3 hrs | 6-8 hrs |
Tolerance
Tolerance Decay
No clear evidence of clinically meaningful tolerance with daily CBDV over weeks to months in limited trials/anecdotes; if present, likely mild and reversible. Cross‑tolerance with CBD is plausible due to overlapping mechanisms, but magnitude is uncertain.
Cross-Tolerances
Effects
- Mild anxiolysis
- Decreased seizure frequency
- Reduced inflammation or pain
- Subtle mood elevation
- Enhanced mental clarity or focus
- Very low or absent intoxication
Combinations
Cross-Check CBDV with another substanceHelpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for CBDV? Let us know. Reports are reviewed by moderators — this is not posted publicly.