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    CBV Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 2 corroborating sources
    • no dose data

    Summary PsychonautWiki

    Cannabis (also known as THC, marijuana, weed, pot, grass, hemp, and many others) is a preparation of the cannabis plant that produces psychoactive effects when consumed (via smoking, vaporizing, or ingestion). It is the most used illicit substance in the world. The mechanism of action is binding activity at cannabinoid receptors distributed throughout the body.

    Tolerance

    Build-up develops over weeks of regular use via CB1 receptor downregulation
    Reset 2–4 weeks for most users; heavy users may need longer

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects

    Positive
    • Stimulation
    • Mental/physical stimulation
    Negative
    • Insomnia
    • Nausea
    • Pupil dilation
    • Increased heart rate
    • Restlessness
    • Muscle tension
    • Sweating/chills
    Neutral
    • Decreased appetite
    Positive
    • Euphoria
    • Wakefulness
    • Empathy
    • Insight
    • Analysis enhancement
    Negative
    • Anxiety
    • Confusion
    Neutral
    • Time distortion
    • Ego softening
    • Change in perception
    Positive
    • Color enhancement
    • Increased music appreciation
    • Enhanced tactile sensation
    • Tracers
    • Tactile enhancement
    • Brightened colour
    • Pattern recognition enhancement
    Neutral
    • Drifting
    • Auditory distortion
    • Closed/Open eye visuals

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