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    Chloroform molecular structure

    Chloroform Stats & Data

    Depressant
    PubChem CID 6212
    NPS DataHub
    MW119.38
    FormulaCHCl3
    CAS67-66-3
    IUPACChloroform
    SMILESClC(Cl)Cl
    InChIKeyHEDRZPFGACZZDS-UHFFFAOYSA-N
    Psychoactive Class Depressant

    Pharmacology

    DrugBank

    Description

    Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and refrigerants, but the latter application is declining.

    Toxicity

    PsychonautWiki PubChem

    This section covers risks general risks for both medical and nonmedical inhalants. For specific risks with nonmedical inhalants, see Toxicity and harm potential for toxic inhalants It is strongly recommended that one use harm reduction practices when using this class of substances. Both medical and nonmedical inhalants should be avoided by:

    LD50

    • LD50: 36 mg/kg (Oral, Mouse) (L138)
    • LD50: 623 mg/kg (Intraperitoneal, Mouse) (L138)
    • LD50: 704 mg/kg (Subcutaneous, Mouse) (L138)

    Carcinogenicity

    Group 2B: Possibly carcinogenic to humans

    Addiction & dependence

    The chronic use of many inhalants can be considered moderately addictive with a high potential for abuse and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and withdrawal effects may occur if a person suddenly stops their usage.

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Experience Report Analysis

    Erowid
    11 Reports
    2001–2017 Date Range
    2 With Age Data
    5 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 11 experience reports (11 Erowid)

    11 Reports
    5 Effects Detected
    2 Positive
    1 Adverse
    2 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 2

    Sedation 27.3% 70%
    Tactile Enhancement 27.3% 70%

    Adverse Effects 1

    Headache 45.5% 70%

    Real-World Dose Distribution

    62K Doses

    From 4 individual dose entries

    Form / Preparation

    Most common forms and preparations reported

    Read full reports on Erowid →
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