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    Chlorphentermine molecular structure

    Chlorphentermine Stats & Data

    NPS DataHub
    MW183.68
    FormulaC10H14ClN
    CAS461-78-9
    IUPAC1-(4-chlorophenyl)-2-methylpropan-2-amine
    SMILESClc1ccc(cc1)CC(C)(C)N
    InChIKeyZCKAMNXUHHNZLN-UHFFFAOYSA-N
    Phenethylamines; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Psychoactive Class Stimulant

    Pharmacology

    DrugBank
    Half-life 40 hours State Solid

    Description

    A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223)

    Pharmacodynamics

    Chlorphentermine is a relatively weak stimulant with little abuse potential. It presents a prominent serotonergic profile leading to pulmonary hypertension and cardiac fibrosis after prolonged use. Thus, this drug is no longer used.

    Absorption

    Well absorbed following oral administration.

    Indication

    Used as an appetite suppressant.

    Effect Profile

    Curated
    Stimulant 6.5

    Strong euphoria and anxiety/jitters with moderate focus and stimulation

    Stimulation / Energy×3
    6
    Euphoria / Mood Lift×2
    10
    Focus / Productivity×2
    7
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d
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