Cloxazolam
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
Summary
Benzodiazepine derivate that is metabolised into Delorazepam. Which is where most of its effects come from.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 1.5-3mg | 3-6mg | 6-12mg | 12mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 15-45 min | 7-12 hrs | 7-12 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Benzodiazepine
7.1
Strong+
7/10
Strong euphoria and anxiolysis with mild sedation and cognitive impairment
Anxiolysis
×3
8
anxiety suppression
reduced anxiety
muscle relaxation
Sedation / Relaxation
×2
5
sedation
muscle relaxation
Motor / Cognitive Impairment
×1
4
amnesia
double vision
Euphoria / Mood Lift
×1
10
cognitive euphoria
euphoria
physical euphoria
disinhibition
Based on reports from:
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Tolerance Decay
Full tolerance
3d
Half tolerance
37d
Baseline
~60d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Positive
- Stimulation
- Physical euphoria
- Muscle relaxation
Negative
- Motor impairment
- Increased heart rate
- Nausea
- Respiratory depression
- Vasoconstriction
- Teeth grinding
- Sedation
Positive
- Reduced anxiety
- Cognitive euphoria
- Euphoria
- Anxiety suppression
Negative
- Compulsive redosing
- Anxiety
- Thought deceleration
- Dizziness
- Amnesia
- Time distortion
Positive
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
Negative
- Disinhibition
- Light sensitivity
- Dehydration
- Appetite suppression
- Double vision
- Dulled perception
Combinations
Cross-Check Cloxazolam with another substance
Cloxazolam's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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