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    Disclaimer
    Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Codeine Well-documented
    Well-documented
    Multiple authoritative sources agree on dosing and effects.
    • 6 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 19 combo interactions documented
    • PubChem toxicity data

    Aliases: Act, Dmo, Dex, Lean, Purp

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    Codeine (also known as 3-Methylmorphine) is a naturally-occurring opioid substance of the morphinan class found in extracts of the poppy, particularly Papaver bracteatum. Members of this group produce effects such as sedation, cough suppression, and euphoria when administered. Codeine is the second most predominant alkaloid in opium (up to three percent).

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-150mg 150-200mg 200mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-45 min 30-60 min 1-2 hrs 2-4 hrs 4-12 hrs 3-6 hrs

    Opioid MME Calculator

    ⚠ Citation & Disclaimer: Conversion factors sourced from the NIH HEAL Initiative MME Calculator (Adams et al., PAIN 2025), the CDC 2022 Clinical Practice Guideline for Prescribing Opioids for Pain, and the MDCalc MME Calculator. These are approximate equianalgesic ratios for educational reference only. Individual responses vary significantly based on genetics, tolerance, cross-tolerance, and route of administration. This is not medical advice. Do not use these conversions to adjust opioid dosing without professional medical guidance.
    mg
    66.7 mg Codeine
    mg Morphine

    ⚠ Equianalgesic dose ratios are approximations and do not account for genetic factors, tolerance, incomplete cross-tolerance, or pharmacokinetic variations. Methadone conversion is especially variable at higher doses. Always consult a healthcare provider before making any changes to opioid therapy.

    Effect Profile

    260 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 198 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 8.3
    Intense 8/10

    Strong euphoria, pain relief, itching/nausea, and sedation

    Euphoria / Warmth ×3
    10
    physical euphoria cognitive euphoria euphoria mood lift
    Analgesia ×2
    10
    pain relief analgesia
    Sedation / Relaxation ×1
    8
    sedation physical relaxation
    Itching / Nausea ×1
    10
    nausea constipation dry mouth

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 5d Half tolerance 7d Baseline ~14d

    Opioid tolerance builds rapidly with near-daily use and decays over weeks. Loss of tolerance after short breaks markedly increases overdose risk if returning to prior ‘pour’ sizes. Data are approximate and largely based on general opioid patterns rather than promethazine/codeine–specific studies.

    Cross-Tolerances

    Effects Erowid Bluelight

    Aggregated from 198 Erowid and 62 Bluelight experience reports

    Positive Effects 48

    Contentment 58.0% 85%
    Euphoria 46.4% 87%
    Sedation 37.1% 88%
    Anxiety Suppression 26.2% 85%
    Heaviness 26.0% 85%
    Warmth 26.0% 91%
    Music Enhancement 25.8% 86%
    Drowsiness 24.0% 85%
    Thought Deceleration 22.0% 78%
    Empathy 21.0% 78%
    Time Dilation 20.0% 80%
    Peace 20.0% 84%
    Vivid Dreams 18.0% 83%
    Stimulation 17.3% 70%
    Body High 16.5% 88%
    Numbness 14.0% 79%
    Bliss 12.0% 88%
    Relaxation 12.0% 89%
    Focus Enhancement 10.9% 70%
    Hypersomnia 10.0% 88%

    Adverse Effects 40

    Itching 42.0% 89%
    Nausea 30.6% 85%
    Dizziness 18.0% 81%
    Dry Mouth 18.0% 81%
    Tactile Enhancement 14.9% 83%
    Confusion 14.1% 70%
    Hot Flashes 14.0% 89%
    Vomiting 12.0% 88%
    Headache 10.1% 78%
    Body Load 10.0% 74%
    Stomach Cramps 8.0% 82%
    Memory Suppression 6.1% 70%
    Panic 6.0% 87%
    Disrupted Sleep Architecture 6.0% 83%
    Ataxia 6.0% 85%
    Sweating 4.0% 86%
    Flushing 4.0% 88%
    Paranoia 4.0% 85%
    Fear 4.0% 88%
    Patterning 4.0% 78%

    Combinations TripSit

    Cross-Check Codeine with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 8 reports 3 positive 3 neutral 2 cautionary visit
    An Incredible Buzz? positive exp #27852

    The night started out with the acquisition of several Panadeine Forte prescription pills, each containing 30mg of codeine and 500mg of paracetamol (acetaminophen); having taken four I went downstairs, downed all four with a glass of water and went into my bedroom with the lights off to wait for the effects.

    Sour Lemon · 120 mg oral / 2000 mg oral / 1 cig. smoked
    What a Beautiful Drug It Is positive exp #65891

    Ah, codeine! What a beautiful drug it is. I realise that there are many people who look down on those who use codeine as a recreational drug because it is such a 'soft-core drug', but I'm here to say that it certainly does have potential to make for a very, very relaxing and euphoric high.

    Anonymo the Wise · repeated oral
    Back to My Love positive exp #76699

    Let me say that my drug/s of choice have always been opioids. (At least since I discovered them) and my favorite amongst them has been codeine. (I live in India, the only other real choice is heroin, since they don’t sell the oxycodones and hydrocodones here, though there are some milder choices like tramadol) But I lo...

    C
    Like My Closest Friend neutral exp #75372

    I’ve been using codeine recreationally for upwards of 13 years now on and off. My initial exposure to it was through my mother who happens to be a nurse, I was about 14 and had a pounding migraine nothing was touching and my mom, being the caring person she is, gave me a Tylenol 2 to help.

    Andrew · Codeine (with Aspirin) · rectal / rectal
    Far Too Much Codeine neutral exp #91704

    My younger brother got prescribed a bottle of Codeine Phosphate solution after he got his tonsils taken out, but my mother didn't give him any because she assumed he was too young to take it, being 6 at the time.

    Codeinated · 750 mg oral
    Fake Tranquility neutral exp #24213

    My story with opiates begins when I was 12. I had a hernia surgery, asked for a painkiller afterwards, and got morphine (IV)... I remember getting scared when I saw the label on the syringe...

    Fylhtq · 100 mg oral
    A Feeling of Calm cautionary exp #52388

    A Feeling of Calm Background: I'm a fairly light 'drugs user' and drinker. I'm a 17 year old male and smoke roughly 10 cigarettes a week. Past experimentation has been with psilocybin (magic mushrooms), caffeine (over dose), marijuana and Hawaiian baby wood rose seeds.

    Jow · 200 mg oral
    An Overdose on My Favorite cautionary exp #45456

    This is the story of my experiences with my favorite drug, codeine, and in particular, my only serious overdose. I first experimented with darvocet after I got a prescription due to problems with my sciatic nerve and extreme lower back pain.

    Ed · Codeine (with Acetaminophen) · 120 mg oral / repeated oral
    Bluelight 8 threads 7 neutral 1 cautionary visit
    Codeine 30mg Experience neutral

    Well let me start by saying that this shit is fucking awesome. I got prescribed tylenol 3 for my wisdom tooth extraction and after seeing that it was a prescription for codeine I was thrilled. I am not a user of opiates so I had no idea what it would be like.

    scraped 2026-03-14
    Codeine 350mg The Good The Bad And The Itchy neutral

    Yesterday, I had a very long dream about using codeine recreationally, as I have been very interested in opiates recently, and I'd like to see what everyone thinks about this.

    scraped 2026-03-14
    Codeine First Time Pukeine neutral

    A few months ago, a good friend from France sent me a message on Facebook and told me that he is gonna spend a day in the city where Im living. I was very glad to hear that because I havent seen him for quite a while.

    scraped 2026-03-14
    Codeine Semi Exp Everything In Its Right Place neutral

    Codeine ~ Semi-Exp ~ Everything In Its Right Place [kat's first trip report] Date of experience: 23/07/04 Substances consumed: Codeine - Pandeine Forte tablets x6 - total 180mg Also coming to the party - Nitrous Alcohol Phenergan (antihistamine) x2 I have used codeine on probably 6 - 8 occasions in the past, up to a do...

    scraped 2026-03-14
    Codeine Semi Exp Everything In Its Right Place neutral

    Codeine ~ Semi-Exp ~ Everything In Its Right Place [kat's first trip report] Date of experience: 23/07/04 Substances consumed: Codeine - Pandeine Forte tablets x6 - total 180mg Also coming to the party - Nitrous Alcohol Phenergan (antihistamine) x2 I have used codeine on probably 6 - 8 occasions in the past, up to a do...

    scraped 2026-03-14
    Codeine 153 6mg Ingested Incrementally Second Time Just Sweet Sweet Codeine neutral

    Just sweet sweet Codeine (153.6mg ingested incrementally) I have tried all sorts of drugs and my only experience with opiates/codeine was having two Panadiene Forte tablets (60mg codeine) on one occasion when I had razors down my throat (not really, just a fucking sore throat).

    scraped 2026-03-14
    Codeine Experienced Bad Codeine Experience neutral

    Amount taken 3000mgs of codeine or 91 32 mg tablets pure codeine all broken in half and swallowed in one gulp Effects start happening around an hour i thought it was 20 minutes but now its later i realise it was more like an hour then i laid down felt quite good i put some music on and stupidly started dancing as i do...

    scraped 2026-03-14
    Codeine 5th Time It Truly Takes 5 Times To Enjoy cautionary

    Codeine - It truly takes 5 exp/times to enjoy My 5 th time tonite. What started off looking like my 4th time a bad trip, came out to be a fine sensation. The onset of a black out / paranoia about a loss of consciiousness as stated in the overdose section of the med booklet was taken under control by aproching the feeli...

    scraped 2026-03-14

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