Cychlorphine
Aliases: Cychlorophine, N-propionitrile chlorophine
Categories
Summary
Extremely limited pharmacological data; field samples frequently contain co-contaminants including xylazine or chlorphine. Standard fentanyl test strips yield false-negatives for benzimidazolone opioids. Naloxone may have reduced effectiveness for reversal of toxicity. Use volumetric dosing with analytical scales and have naloxone immediately available.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects |
|---|---|---|---|---|
| Oral | 5-15 min | 30-90 min | 3-6 hrs | 2-6 hrs |
| Insufflated | 5-15 min | 30-90 min | 3-6 hrs | 2-6 hrs |
| Intravenous | 1-5 min | 30-90 min | 3-6 hrs | 2-6 hrs |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Effects
Positive
- Analgesia
- Anxiolysis
- Physical euphoria
- Pain relief
Negative
- Respiratory depression
- Pruritus
- Nausea
- Sedation
- Miosis
- Itchiness
Positive
- Euphoria
- Reduced anxiety
- Cognitive euphoria
- Anxiety suppression
- Wakefulness
- Motivation enhancement
Negative
- Constipation
- Compulsive redosing
- Motivation suppression
- Anxiety
Positive
- Warmth
- Increased music appreciation
- Increased libido
Negative
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dehydration
- Dulled perception
- Internal hallucination
- Warm flush