Cyproheptadine
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- dose data not in PW/TripSit (unverifiable)
- 1 source
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
- dose data not in PW/TripSit (unverifiable)
Aliases: Reactin, Apeplus, Biohept, Periatin, Periactin
Summary
For serotonin syndrome management: administer a 12 mg oral loading dose, then 2 mg every 2 hours until clinical improvement (max 32 mg/24 hours); thereafter give 4-8 mg every 6 hours as needed. Monitor for over-sedation, urinary retention, delirium, and hepatic enzymes in prolonged courses. May interfere with hemostasis and prolong bleeding time.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 4-8mg | 8-12mg | 16-20mg | 24-32mg |
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | Total |
|---|---|---|---|---|
| Oral | 30-60 min | 2-6 hrs | 8-12 hrs | 4-12 hrs |
Tolerance
Tolerance Decay
Users commonly report tolerance to the sedative effect developing over several days of continuous use and partial reversal over weeks after cessation; robust quantitative data are lacking.
Effects
- Appetite Stimulation
- Antipruritic Relief
- Muscle relaxation
- Dry Mouth
- Motor Coordination Suppression
- Dry mouth
- Increased heart rate
- Muscle cramps
- Nausea
- Sedation
- Relaxation
- Reduced anxiety
- Drowsiness
- Cognitive Impairment
- Delirium
- Confusion
- Dysphoria
- Anxiety
- Paranoia
- Dizziness
- Blurred Vision
- Blurred vision
- Dulled perception
- External hallucinations
- Internal hallucinations
- Visual and audio distortions
- Perception of Bodily Heaviness
- External Hallucination
- Auditory Hallucination
- External hallucination
Pill Identifiers
Helpful Links
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