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    Dehydroxyfluorafinil molecular structure

    Dehydroxyfluorafinil Stats & Data

    Fiendz Modafiendz N-methylbisfluoromodafinil
    NPS DataHub
    MW323.36
    FormulaC16H15F2NO2S
    CAS1613222-54-0
    IUPAC2-[bis(4-fluorophenyl)methylsulfinyl]-N-methylacetamide
    SMILESCNC(=O)CS(=O)C(c1ccc(F)cc1)c1ccc(F)cc1
    InChIKeyMQZWTCIUDSDFCQ-UHFFFAOYSA-N
    Psychoactive Class Stimulant
    Half-Life Estimated 10–15 h (analogy to modafinil; analogue-specific data lacking)

    Interaction Warnings

    mdma

    The neurotoxic effects of MDMA may be increased when combined with other stimulants.

    cocaine

    This combination may increase strain on the heart.

    Receptor Profile

    Receptor Actions

    Inhibitors
    Atypical dopamine reuptake inhibitor

    Effect Profile

    Curated
    Stimulant 4.8

    Strong focus and anxiety/jitters with mild stimulation, low euphoria

    Stimulation / Energy×3
    5
    Euphoria / Mood Lift×2
    2
    Focus / Productivity×2
    9
    Anxiety / Jitters×1
    9

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Estimated 10–15 h (analogy to modafinil; analogue-specific data lacking)
    Addiction Potential
    Low to moderate; comparable to modafinil but subject to individual variability

    Tolerance Decay

    Full tolerance 7d Half tolerance 3d Baseline ~14d

    Patterns extrapolated from modafinil‑class anecdotal use; daily use for 1–2 weeks often blunts effects, with partial reversal after 3–5 days off and near‑baseline after 2–4 weeks. Data quality is anecdotal, individual variability is high.

    Cross-Tolerances

    Modafinil
    50% ●○○
    Armodafinil
    50% ●○○
    Flmodafinil
    50% ●○○
    Fladrafinil
    40% ●○○

    Harm Reduction

    drugs.wiki

    Name/identity: This compound has been sold as “Modafiendz” and discussed as N‑methyl‑4,4'-difluoromodafinil; there is no peer‑reviewed human PK/toxicology, and marketed products may contain variable or mislabelled actives. User reports range from minimal effects to notable palpitations, highlighting batch inconsistency and possible adulteration or degradation. If the analogue shares modafinil’s liabilities, rare but serious cutaneous reactions (e.g., SJS/TEN/DRESS) are a concern; discontinue immediately at any rash or mucosal symptoms. Modafinil‑like CYP effects (3A4 induction; 2C19 inhibition) can meaningfully alter other drugs (e.g., methadone, diazepam) and potentially reduce effectiveness of some hormonal contraceptives—use extra protection while using and for weeks after, pending more data. Cardiovascular strain (tachycardia, BP elevation) and anxiety are reported; those with heart disease, arrhythmia history, or panic disorders should avoid or use only with medical oversight. Residual wakefulness can impair sleep architecture for 6–12 h after offset; avoid late dosing and plan sleep hygiene. Avoid combining with other stimulants or high caffeine to limit BP/HR spikes and jitteriness. Do not snort or inject: modafinil‑class compounds are poorly water soluble and not formulated for non‑oral routes; non‑oral use increases harm without added benefit. Due to frequent mislabeling in the unregulated market, consider drug checking where available; basic reagents are not definitive for this class, but MS‑based services can confirm composition. Until human data exist, treat all dosing guidance as provisional and titrate cautiously.

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